Multimodal endovascular reperfusion therapies: adjunctive antithrombotic agents in acute stroke. Neurology 2012 Feb 14;78(7):501-6
Date
02/15/2012Pubmed ID
22330414DOI
10.1212/WNL.0b013e318246d6a5Scopus ID
2-s2.0-84858117098 (requires institutional sign-in at Scopus site) 6 CitationsAbstract
Pharmacologic and mechanical endovascular acute ischemic stroke therapy aims to recanalize occluded cerebral vessels to achieve improved clinical outcome. Several limitations to achieving this goal have been identified; one of the least discussed challenges in the literature is reocclusion. The intraprocedure and periprocedural roles of anticoagulation and antiplatelet agents in preventing reocclusion are unclear. In this review, the role of antiplatelet and anticoagulation agents as an adjunctive to acute ischemic stroke endovascular revascularization therapy is discussed.
Author List
Lazzaro MA, Zaidat OOAuthor
Marc A. Lazzaro MD Associate Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Administration, OralAnticoagulants
Endovascular Procedures
Fibrinolytic Agents
Hemostasis
Humans
Injections, Intravenous
Platelet Aggregation Inhibitors
Reperfusion
Stroke
Thrombolytic Therapy