Target-driven acquisition and super-resolution reconstruction for magnetic resonance imaging. Magn Reson Imaging 2026 Jul;130:110675
Date
04/01/2026Pubmed ID
41916155DOI
10.1016/j.mri.2026.110675Scopus ID
2-s2.0-105034137071 (requires institutional sign-in at Scopus site)Abstract
At the time of magnetic resonance imaging guided radiation therapy treatment delivery, the location of the target volume has been well established. During treatment of abdominal and thoracic tumors, real-time localization of the target using MRI is employed as a safety assurance measure. While high frame rate 3D imaging is desired for real-time localization, the inherently slow data collection speed of MRI limits the acquisition to planar 2D imaging intersecting the target. With this approach, the delivery can be paused if the target moves too far away from its ideal treatment position, but a volumetric history of the position of the target for each instance during delivery is lost. In this work, we develop a novel 2D multislice MRI encoding scheme in which every prescribed slice intersects the treatment target. With this approach, the rotating 2D slice always captures the position of the target for safety assurance, but a combined parallel imaging and super-resolution reconstruction can be used to produce 3D volumes in high detail near the target and lesser detail further away from the target. This novel encoding and reconstruction framework was demonstrated in phantom and in vivo experiments at 3T.
Author List
Mickevicius NJ, Paulson ESAuthor
Eric Paulson PhD Chief, Professor in the Radiation Oncology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AlgorithmsHumans
Image Enhancement
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Phantoms, Imaging
Radiotherapy, Image-Guided
Reproducibility of Results
