Interspecies comparison of mucosal wave properties using high-speed digital imaging. Laryngoscope 2010 Jun;120(6):1188-94
Date
06/01/2010Pubmed ID
20513038Pubmed Central ID
PMC3212406DOI
10.1002/lary.20884Scopus ID
2-s2.0-77953165509 (requires institutional sign-in at Scopus site) 30 CitationsAbstract
OBJECTIVES/HYPOTHESIS: The purpose of this study was to compare the vocal fold vibratory characteristics of ex vivo bovine, canine, ovine, and porcine larynges to human male and female vocal fold vibrations to determine the best model organism for laryngeal studies concerning vibratory and kinetic characteristics.
STUDY DESIGN: Prospective experimental.
METHODS: High-speed videos of phonation were gathered at 4,000 frames per second (fps) in the animal models and human high-speed endoscopy data were gathered at 2,000 fps. Videos were converted into kymograms, and the amplitude, oscillation frequency, and phase difference of vocal fold vibration were measured.
RESULTS: No statistically significant differences were found with respect to frequency, amplitude, or phase difference between canines and humans. Porcines were not significantly different from human females but did have an oscillation frequency significantly different from human males. Ovine vibrational amplitudes were significantly different from humans, and bovine frequency and amplitude differed significantly from humans.
CONCLUSIONS: Canine and porcine larynges are the most appropriate model specimens for laryngeal studies contingent on vibratory or kinetic properties of phonation.
Author List
Regner MF, Robitaille MJ, Jiang JJAuthor
Michael Regner MD Associate Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Analysis of VarianceAnimals
Cattle
Dogs
Female
Humans
Kymography
Laryngoscopy
Male
Models, Animal
Mucous Membrane
Phonation
Prospective Studies
Sheep
Signal Processing, Computer-Assisted
Swine
Vibration
Video Recording
Vocal Cords
