Orbital granuloma annulare as presentation of systemic sarcoidosis. Orbit 2013 Dec;32(6):372-4
Date
07/31/2013Pubmed ID
23895369Pubmed Central ID
PMC4111453DOI
10.3109/01676830.2013.812125Scopus ID
2-s2.0-84887975145 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
PURPOSE: To report a unique case of an orbital mass with atypical histopathologic features that although overlap with other granulomatous disorders, likely represents orbital involvement of systemic sarcoidosis.
METHODS: Observational case report.
RESULTS: A 51-year-old woman presented with an orbital mass and was found to have mild proptosis and restriction of ocular motility. The remainder of her ophthalmic exam was unremarkable. Excisional biopsy revealed ill-defined granulomas with central necrosis, chronic inflammation and sclerotic collagen; several features consistent with granuloma annulare. Further systemic workup including laboratory and radiologic studies were compatible with a diagnosis of systemic sarcoidosis.
CONCLUSION: Our case emphasizes the importance of a complete systemic workup with the detection of an orbital granuloma to ensure accurate diagnosis and appropriate management.
Author List
Kang JJ, Aakalu VK, Lin A, Setabutr PAuthor
Vinay Kumar Aakalu MPH, MD Chair, Professor in the Ophthalmology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BiopsyExophthalmos
Female
Granuloma Annulare
Humans
Magnetic Resonance Imaging
Middle Aged
Ocular Motility Disorders
Orbital Diseases
Sarcoidosis
Tomography, X-Ray Computed
