Crohn Disease Presenting as Vaginal Discharge in a Patient With Systemic Lupus Erythematosus. Pediatrics 2026 Jul 01;158(1)
Date
06/17/2026Pubmed ID
42303253DOI
10.1542/peds.2025-073979Scopus ID
2-s2.0-105043461194 (requires institutional sign-in at Scopus site)Abstract
Crohn disease (CD), a subtype of inflammatory bowel disease, may be complicated by extraintestinal manifestations. Although cutaneous findings are among the most frequent, metastatic Crohn disease (MCD), defined as mucocutaneous CD at sites noncontiguous with the gastrointestinal tract, is rare. Children with MCD are more likely than adults to develop genital inflammation. Case reports describe the vulva, scrotum, and penis as common locations of involvement in children with genital MCD. We report a case of a pediatric patient with systemic lupus erythematosus who developed vaginal discharge as a presenting symptom of MCD in the absence of an anorectal-vaginal fistula. We describe an unusual combination of clinical features and intend to improve awareness of uncommon extraintestinal manifestations of CD.
Author List
Ries AG, Samalik J, Nocton JJ, Francis J, Arkin LM, Seroogy CM, Young KE, Chiu YEAuthors
Yvonne E. Chiu MD Vice Chair, Professor in the Dermatology department at Medical College of WisconsinJames J. Nocton BS, MD Vice-Chair, Professor in the Pediatrics department at Medical College of Wisconsin
Joann M. Samalik BS, MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
ChildCrohn Disease
Diagnosis, Differential
Female
Humans
Lupus Erythematosus, Systemic
Vaginal Discharge
