Foxp3: shades of tolerance. Immunity 2012 May 25;36(5):693-4
Date
05/29/2012Pubmed ID
22633453Pubmed Central ID
PMC3868336DOI
10.1016/j.immuni.2012.05.011Scopus ID
2-s2.0-84861430203 (requires institutional sign-in at Scopus site) 5 CitationsAbstract
In this issue of Immunity, Darce et al. (2012) and Bettini et al. (2012) demonstrate that seemingly subtle alterations in the interaction of Foxp3 with its transcriptional partners have a ripple effect on the outcome of autoimmune phenotypes, worsening some while ameliorating others.