Molecular mechanisms regulating persistent Mycobacterium tuberculosis infection. Microbes Infect 2003 Feb;5(2):159-67
Date
03/26/2003Pubmed ID
12650774DOI
10.1016/s1286-4579(02)00083-7Scopus ID
2-s2.0-0037296604 (requires institutional sign-in at Scopus site) 72 CitationsAbstract
Establishing persistent infection and resisting elimination by the host's immune system are key factors contributing to latent infection by Mycobacterium tuberculosis. Recently, bacterial determinants regulating these processes have been identified. Here, we review molecular mechanisms regulating persistent infection and discuss the highly dynamic interaction of M. tuberculosis with the host.
Author List
Zahrt TCMESH terms used to index this publication - Major topics in bold
AnimalsBacterial Proteins
Carrier State
Disease Models, Animal
Gene Expression Regulation, Bacterial
Granuloma
Humans
Macrophages
Mice
Mycobacterium tuberculosis
Tuberculosis
Virulence