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Obstetrical and perinatal outcomes among women with gestational hypertension, mild preeclampsia, and mild chronic hypertension. Am J Obstet Gynecol 2011 Sep;205(3):260.e1-9

Date

11/11/2011

Pubmed ID

22071056

DOI

10.1016/j.ajog.2011.06.033

Scopus ID

2-s2.0-80052211329 (requires institutional sign-in at Scopus site)   59 Citations

Abstract

OBJECTIVE: The purpose of this study was to compare maternal and neonatal outcomes of women with gestational hypertension (GHTN), mild chronic hypertension (CHTN), and mild preeclampsia at delivery.

STUDY DESIGN: A multicenter database that contained 228,668 deliveries was used to extract data on gravid women with GHTN, preeclampsia, and CHTN and on women without hypertensive disease (control group). Univariate and multivariate logistic regression analyses were performed.

RESULTS: There were 4918 women with GHTN, 5274 women with preeclampsia, 2531 women with CHTN, and 15,221 control subjects. Women with GHTN had the greatest risk for blood transfusion (adjusted odds ratio [aOR], 4.6; 95% confidence interval [CI], 3.4-6.3), intensive care unit admission (aOR, 25.7; 95% CI, 9.8-67.3), and lowest risk for stillbirth (aOR, 0.1; 95% CI, 0.04-0.4); women with preeclampsia had the greatest risk for postpartum hypertension (aOR, 9.6; 95% CI, 7.2-12.9). Neonates with GHTN had the greatest risk for ventilator requirements (aOR, 7.5; 95% CI, 4.6-12.4).

CONCLUSION: Women with gestational hypertension and their neonates had significant risks for morbidity, compared with women with mild chronic hypertension and those with mild preeclampsia.

Author List

Cruz MO, Gao W, Hibbard JU

Authors

Meredith Cruz MD Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin
Judith Hibbard Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Databases, Factual
Female
Humans
Hypertension
Hypertension, Pregnancy-Induced
Infant, Newborn
Male
Pre-Eclampsia
Pregnancy
Pregnancy Outcome
Retrospective Studies
Severity of Illness Index