Irrigation pressure and vessel injury during microsurgery: a qualitative study. J Reconstr Microsurg 2004 Jul;20(5):399-403
Date
07/09/2004Pubmed ID
15237359DOI
10.1055/s-2004-830004Scopus ID
2-s2.0-3142777688 (requires institutional sign-in at Scopus site) 5 CitationsAbstract
Irrigation solution is routinely used in microsurgery. While the anticoagulation solution may aid in anastomotic patency, the direct effect of pressure irrigation can have a detrimental effect on the vessel. An experimental study was performed to determine the effect of irrigation pressure on the vessel wall. Histological evaluation with hematoxylin and eosin (H&E) stain and scanning electron microscopy (SEM) was performed on the arteries of New Zealand white rabbits irrigated with lactated Ringer's solution at pressures of 80 mmHg, 100 mmHg, and 500 mmHg. H&E staining and SEM microscopy demonstrated injury to the endothelial cells and internal elastic lamina at pressures of 100 mmHg or greater. Controlling microsurgical irrigation pressure to less than 100 mmHg may help to avoid vessel injury.
Author List
Yan JG, Yousif NJ, Dzwierzynski WW, Matloub HS, Sanger JR, Shehadi IE, Siegesmund KAAuthors
William W. Dzwierzynski MD Professor in the Plastic Surgery department at Medical College of WisconsinHani S. Matloub MD Professor in the Plastic Surgery department at Medical College of Wisconsin
James R. Sanger MD Professor in the Plastic Surgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AnimalsEndothelium, Vascular
Microsurgery
Pressure
Rabbits
Therapeutic Irrigation
