Congenital mydriasis associated with megacystis microcolon intestinal hypoperistalsis syndrome. J Neuroophthalmol 2013 Sep;33(3):271-5
Date
05/03/2013Pubmed ID
23636104DOI
10.1097/WNO.0b013e31828b7d65Scopus ID
2-s2.0-84883554704 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
We report a case of congenital mydriasis in a neonate with megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS). Pilocarpine testing and gastrointestinal pathology in our patient suggest that the mydriasis is due to an underlying smooth muscle myopathy of the iris sphincter muscle. These findings may have important implications regarding the pathogenesis of MMIHS.
Author List
McClelland C, Walsh RD, Chikwava KR, Johnson MP, Mattei P, Liu GTAuthor
Ryan Walsh MD Associate Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Abnormalities, MultipleColon
Eye Diseases, Hereditary
Female
Humans
Intestinal Pseudo-Obstruction
Muscle, Smooth
Mydriasis
Urinary Bladder
Young Adult