Onyx embolization of infectious intracranial aneurysms. J Neurointerv Surg 2014 Jun;6(5):353-6
Date
05/07/2013Pubmed ID
23645573DOI
10.1136/neurintsurg-2013-010755Scopus ID
2-s2.0-84901923117 (requires institutional sign-in at Scopus site) 26 CitationsAbstract
BACKGROUND: Infectious intracranial aneurysms (IIAs) are rare and potentially devastating. First-line management involves intravenous antibiotics, with surgical or endovascular management reserved for cases of failed medical treatment or aneurysmal rupture. Endovascular therapy has become the primary approach for treating these small, distally located aneurysms. Liquid embolic agents are well suited for use because of their ability to fill the aneurysm and parent vessel. We present our experience in treating these aneurysms via Onyx embolization and review the literature.
METHODS: We retrospectively reviewed the endovascular treatment of IIAs at our institution from 2010 to 2012. Eight patients with 16 IIAs ranging in size from 1 to 16 mm underwent treatment. Seven of the patients initially presented after aneurysmal rupture. Onyx was pushed until the aneurysm and parent artery were filled. Confirmation of aneurysmal occlusion was made by repeat cerebral angiography.
RESULTS: One symptomatic stroke occurred after embolization. Fourteen of the 16 aneurysms have been evaluated with follow-up angiography and remain occluded.
CONCLUSIONS: Treatment of IIAs using an endovascular approach with Onyx is safe and effective.
Author List
Grandhi R, Zwagerman NT, Linares G, Monaco EA 3rd, Jovin T, Horowitz M, Jankowitz BTAuthor
Nathan Zwagerman MD Associate Professor in the Neurosurgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAneurysm, Infected
Cerebral Angiography
Drug Combinations
Embolization, Therapeutic
Follow-Up Studies
Humans
Intracranial Aneurysm
Middle Aged
Polyvinyls
Retrospective Studies
Tantalum
Tomography, X-Ray Computed
Treatment Outcome
Young Adult
