Serotonin syndrome induced by transitioning from phenelzine to venlafaxine: four patient reports. Neurology 1998 Jul;51(1):274-6
Date
07/23/1998Pubmed ID
9674820DOI
10.1212/wnl.51.1.274Scopus ID
2-s2.0-0032109624 (requires institutional sign-in at Scopus site) 18 CitationsAbstract
With the use of the newer antidepressants beyond the traditional tricyclics and monoamine oxidase inhibitors, newer options in headache prophylaxis are provided as well as the potential for undesirable and even potentially life-threatening interactions between medications. In this article, four patient reports of a specific interaction--the serotonin syndrome--are presented. These events resulted from transitioning headache patients from an older antidepressant (phenelzine) to a newer antidepressant (venlafaxine).
Author List
Diamond S, Pepper BJ, Diamond ML, Freitag FG, Urban GJ, Erdemoglu AKMESH terms used to index this publication - Major topics in bold
AdultCentral Nervous System Diseases
Cyclohexanols
Drug Interactions
Female
Humans
Male
Middle Aged
Migraine Disorders
Monoamine Oxidase Inhibitors
Phenelzine
Serotonin
Venlafaxine Hydrochloride
