Faculty Collaboration Database

Pharmacological approaches to managing migraine and associated comorbidities--clinical considerations for monotherapy versus polytherapy. Headache 2007 Apr;47(4):585-99

Date

04/21/2007

Pubmed ID

17445108

DOI

10.1111/j.1526-4610.2007.00760.x

Scopus ID

2-s2.0-34247341837 (requires institutional sign-in at Scopus site)   67 Citations

Abstract

Comorbidity is defined as an illness that occurs more frequently in association with a specific disorder than would be found as a coincidental association in the general population. Conditions that are frequently comorbid with migraine include depression, anxiety, stroke, epilepsy, sleep disorders, and other pain disorders. In addition, many common illnesses occur concomitantly (at the same time) with migraine and influence the treatment choice. Migraine management, and especially migraine prevention, can be challenging when patients have comorbid or concomitant illnesses. The objectives of this initiative are to review the literature on managing patients who have migraine and common comorbidities, present additional clinical approaches for care of these difficult patients, and evaluate the areas in which research is needed to establish evidence-based guidelines for the management of migraine with associated comorbid conditions.

Author List

Silberstein SD, Dodick D, Freitag F, Pearlman SH, Hahn SR, Scher AI, Lipton RB

MESH terms used to index this publication - Major topics in bold

Comorbidity
Drug Therapy, Combination
Humans
Mental Disorders
Migraine Disorders
Obesity
Risk Factors
Sex Factors
Stroke