Lung air spaces: MR imaging evaluation with hyperpolarized 3He gas. Radiology 1999 Mar;210(3):851-7
Date
04/20/1999Pubmed ID
10207491DOI
10.1148/radiology.210.3.r99fe08851Scopus ID
2-s2.0-0032975107 (requires institutional sign-in at Scopus site) 246 CitationsAbstract
Thirty-two magnetic resonance imaging examinations of the lungs were performed in 16 subjects after inhalation of 1-2 L of helium 3 gas that was laser polarized to 10%-25%. The distribution of the gas was generally uniform, with visualization of the fissures in most cases. Ventilation defects were demonstrated in smokers and in a subject with allergies. The technique has potential for evaluating small airways disease.
Author List
de Lange EE, Mugler JP 3rd, Brookeman JR, Knight-Scott J, Truwit JD, Teates CD, Daniel TM, Bogorad PL, Cates GDMESH terms used to index this publication - Major topics in bold
Administration, InhalationAdult
Aged
Asthma
Female
Helium
Humans
Image Processing, Computer-Assisted
Isotopes
Lasers
Lung
Magnetic Resonance Imaging
Male
Middle Aged
Observer Variation
Oxygen
Pulmonary Emphysema
Respiration
Rhinitis, Allergic, Seasonal
Smoking
