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Electroencephalogram coherence in children with and without autism spectrum disorders: decreased interhemispheric connectivity in autism. Autism Res 2014 Jun;7(3):334-43

Date

03/14/2014

Pubmed ID

24623657

DOI

10.1002/aur.1367

Scopus ID

2-s2.0-84902837067 (requires institutional sign-in at Scopus site)   32 Citations

Abstract

Electroencephalogram coherence was measured in children with autism spectrum disorders (ASD) and control children at baseline and while watching videos of a familiar and unfamiliar person reading a story. Coherence was measured between the left and right hemispheres of the frontal, parietal, and temporal-parietal lobes (interhemispheric) and between the frontal and parietal lobes in each hemisphere (intrahemispheric). A data-reduction technique was employed to identify the frequency (alpha) that yielded significant differences in video conditions. Children with ASD displayed reduced coherence at the alpha frequency between the left and right temporal-parietal lobes in all conditions and reduced coherence at the alpha frequency between left and right frontal lobes during baseline. No group differences in intrahemispheric coherence at the alpha frequency emerged at the chosen statistical threshold. Results suggest decreased interhemispheric connectivity in frontal and temporal-parietal regions in children with ASD compared to controls.

Author List

Carson AM, Salowitz NM, Scheidt RA, Dolan BK, Van Hecke AV

Authors

Robert Scheidt BS,MS,PhD Associate Professor in the Biomedical Engineering department at Marquette University
Amy Van Hecke PhD Professor in the Psychology department at Marquette University




MESH terms used to index this publication - Major topics in bold

Brain
Brain Mapping
Child
Child Development Disorders, Pervasive
Electroencephalography
Female
Frontal Lobe
Humans
Male
Parietal Lobe
Temporal Lobe