Cellular and genetic basis of primary immune deficiencies. Pediatr Clin North Am 2006 Aug;53(4):649-84
Date
07/29/2006Pubmed ID
16872998DOI
10.1016/j.pcl.2006.05.005Scopus ID
2-s2.0-33746208998 (requires institutional sign-in at Scopus site) 9 CitationsAbstract
Knowledge of the genetic mutations of primary immune deficiency syndromes has grown significantly over the last 30 years. In this article the authors present an overview of the clinical aspects, laboratory evaluation, and genetic defects of primary immunodeficiencies, with an emphasis on the pathophysiology of the known molecular defects. This article is designed to give the primary pediatrician a general knowledge of this rapidly expanding field.
Author List
Verbsky JW, Grossman WJAuthor
James Verbsky MD, PhD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
HumansImmune System
Immunologic Deficiency Syndromes
Lymphocytes