Renal cystic disease: new insights for the clinician. Pediatr Clin North Am 2006 Oct;53(5):889-909, ix
Date
10/10/2006Pubmed ID
17027616DOI
10.1016/j.pcl.2006.08.012Scopus ID
2-s2.0-33749244497 (requires institutional sign-in at Scopus site) 21 CitationsAbstract
This article cannot comprehensively cover the enormous strides made in defining the molecular and cellular basis of renal cystic diseases over the last decade. Therefore, it provides a brief overview and categorization of inherited, developmental, and acquired renal cystic diseases, providing a relevant, up-to-date bibliography as well as a useful list of informative Internet Web sites. Its major focus is the translational biology of polycystic kidney disease. It demonstrates how emerging molecular and cellular knowledge of the pathophysiology of particular diseases such as autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ADPKD) can translate into innovative therapeutic insights.
Author List
Avner ED, Sweeney WE JrAuthor
Ellis D. Avner MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsApoptosis
Cell Division
Cyst Fluid
ErbB Receptors
Extracellular Matrix
Growth Substances
Humans
Internet
Kidney Diseases, Cystic
Proto-Oncogene Proteins
Signal Transduction
