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Early experience and the development of stress reactivity and regulation in children. Neurosci Biobehav Rev 2010 May;34(6):867-76



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Scopus ID

2-s2.0-77950629125   332 Citations


Children who spend early portions of their lives in institutions or those maltreated in their families of origin are at risk for developing emotional and behavioral problems reflecting disorders of emotion and attention regulation. Animal models may help explicate the mechanisms producing these effects. Despite the value of the animal models, many questions remain in using the animal data to guide studies of human development. In 1999, the National Institute of Mental Health in the United States funded a research network to address unresolved issues and enhance translation of basic animal early experience research to application in child research. Professor Seymour Levine was both the inspiration for and an active member of this research network until his death in October of 2007. This review pays tribute to his legacy by outlining the conceptual model which is now guiding our research studies.

Author List

Loman MM, Gunnar MR, Early Experience, Stress, and Neurobehavioral Development Center


Michelle Loman Moudry PhD Assistant Professor in the Neurology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Child Development
Models, Biological
Stress, Psychological