WMDA guidelines for subsequent donations following initial BM or PBSCs. Bone Marrow Transplant 2011 Nov;46(11):1409-12
Date
02/08/2011Pubmed ID
21297674DOI
10.1038/bmt.2010.323Scopus ID
2-s2.0-80855156683 (requires institutional sign-in at Scopus site) 14 CitationsAbstract
Unrelated donor SCT activity is increasing, and in 5-10% of cases a subsequent donation of stem cells or donor lymphocytes may be requested. Second donations of stem cells are not associated with an increased chance of donor complications, but the yield of CD34+ cells may be lower in some donors. It is acceptable practice for any registry to request subsequent donations and it is recommended that donors should be counselled about this possibility before their first donation. Guidance is provided on the requirements for further medical assessment, the procedures used to agree requests, frequency and timing of donation and timing and duration of donor follow up.
Author List
Confer DL, Shaw BE, Pamphilon DH, Clinical Working Group of the WMDAAuthor
Bronwen E. Shaw MBChB, PhD Center Director, Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Antigens, CD34Bone Marrow Transplantation
Female
Hematopoietic Stem Cells
Humans
Male
Peripheral Blood Stem Cell Transplantation
Registries
Tissue Donors
Tissue and Organ Procurement
Unrelated Donors