Failure of medical therapy despite normal intraocular pressure. Clin Exp Ophthalmol 2006 Dec;34(9):827-36
Date
12/22/2006Pubmed ID
17181612DOI
10.1111/j.1442-9071.2006.01368.xScopus ID
2-s2.0-33845295797 (requires institutional sign-in at Scopus site) 27 CitationsAbstract
The disease glaucoma is now defined by characteristic optic disc and visual field change, without specific reference to the intraocular pressure (IOP). Success of treatment is no longer judged by the mere attainment of IOP less than 21 mmHg. Controversy remains, however, in deciding appropriate management where optic disc and/or visual field damage continues to progress despite a 'normal' IOP having been achieved with medical treatment. A panel of international glaucoma experts has provided management recommendations in four clinical scenarios--open-angle glaucoma, open-angle glaucoma in a myopic contact lens wearer, uveitic glaucoma and open-angle glaucoma in combination with visually significant cataract--where optic nerve and visual field progression has continued despite an IOP less than 21 mmHg on full medical treatment. Surgical intervention with mitomycin trabeculectomy is the most favoured further therapy.
Author List
Walland MJ, Carassa RG, Goldberg I, Grehn F, Heuer DK, Khaw PT, Thomas R, Parikh RAuthor
Dale Heuer MD Emeritus Professor in the Ophthalmology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAntihypertensive Agents
Cataract
Contact Lenses
Disease Progression
Drug Therapy, Combination
Female
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Male
Middle Aged
Myopia
Trabeculectomy
Treatment Failure
Uveitis
Vision Disorders
Visual Fields
