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Neurodevelopmental outcome in preschool survivors of complex congenital heart disease: implications for clinical practice. J Pediatr Health Care 2007;21(1):3-12

Date

01/03/2007

Pubmed ID

17198894

DOI

10.1016/j.pedhc.2006.03.008

Scopus ID

2-s2.0-33845771293 (requires institutional sign-in at Scopus site)   80 Citations

Abstract

INTRODUCTION: The purpose of this study was to describe the neurodevelopmental outcome of preschool survivors of Hypoplastic Left Heart Syndrome (HLHS) and Transposition of the Great Arteries (TGA) in the modern surgical era.

METHODS: A cross-sectional design was used to evaluate 26 children (13 HLHS, 13 TGA), ages 3.5 to 6 years, at a Midwestern children's hospital. Measures included McCarthy Scales of Children's Abilities, Woodcock Johnson III Tests of Achievement, Developmental Test of Visual-Motor Integration, Receptive One-Word Vocabulary Test, Expressive One-Word Vocabulary Test, and Child Behavior Checklist.

RESULTS: Although intelligence quotient scores fell within the average range for both groups (TGA=110.5 vs. HLHS=97), the difference between groups was clinically meaningful (effect size= .79). The HLHS group showed more problems than did the TGA group with visual-motor skills, expressive language, attention, and externalizing behavior.

DISCUSSION: Results suggest that even in the modern surgical era, regular developmental screening for these patients is critical. Pediatric nurse practitioners play an important role in educating parents about the potential developmental risks to these children.

Author List

Brosig CL, Mussatto KA, Kuhn EM, Tweddell JS

Authors

Cheryl L. Brosig Soto PhD Chief, Professor in the Pediatrics department at Medical College of Wisconsin
Kathleen Mussatto Ph.D. Associate Professor in the School of Nursing department at Milwaukee School of Engineering




MESH terms used to index this publication - Major topics in bold

Analysis of Variance
Child
Child, Preschool
Cross-Sectional Studies
Developmental Disabilities
Female
Humans
Hypoplastic Left Heart Syndrome
Male
Mass Screening
Neuropsychological Tests
Postoperative Complications
Transposition of Great Vessels
Wisconsin