Neurodevelopmental outcome in preschool survivors of complex congenital heart disease: implications for clinical practice. J Pediatr Health Care 2007;21(1):3-12
Date
01/03/2007Pubmed ID
17198894DOI
10.1016/j.pedhc.2006.03.008Scopus ID
2-s2.0-33845771293 (requires institutional sign-in at Scopus site) 80 CitationsAbstract
INTRODUCTION: The purpose of this study was to describe the neurodevelopmental outcome of preschool survivors of Hypoplastic Left Heart Syndrome (HLHS) and Transposition of the Great Arteries (TGA) in the modern surgical era.
METHODS: A cross-sectional design was used to evaluate 26 children (13 HLHS, 13 TGA), ages 3.5 to 6 years, at a Midwestern children's hospital. Measures included McCarthy Scales of Children's Abilities, Woodcock Johnson III Tests of Achievement, Developmental Test of Visual-Motor Integration, Receptive One-Word Vocabulary Test, Expressive One-Word Vocabulary Test, and Child Behavior Checklist.
RESULTS: Although intelligence quotient scores fell within the average range for both groups (TGA=110.5 vs. HLHS=97), the difference between groups was clinically meaningful (effect size= .79). The HLHS group showed more problems than did the TGA group with visual-motor skills, expressive language, attention, and externalizing behavior.
DISCUSSION: Results suggest that even in the modern surgical era, regular developmental screening for these patients is critical. Pediatric nurse practitioners play an important role in educating parents about the potential developmental risks to these children.
Author List
Brosig CL, Mussatto KA, Kuhn EM, Tweddell JSAuthors
Cheryl L. Brosig Soto PhD Chief, Professor in the Pediatrics department at Medical College of WisconsinKathleen Mussatto Ph.D. Associate Professor in the School of Nursing department at Milwaukee School of Engineering
MESH terms used to index this publication - Major topics in bold
Analysis of VarianceChild
Child, Preschool
Cross-Sectional Studies
Developmental Disabilities
Female
Humans
Hypoplastic Left Heart Syndrome
Male
Mass Screening
Neuropsychological Tests
Postoperative Complications
Transposition of Great Vessels
Wisconsin