Dissociation of neural regions associated with anticipatory versus consummatory phases of incentive processing. Psychophysiology 2008 Jan;45(1):36-49
Date
09/14/2007Pubmed ID
17850241Pubmed Central ID
PMC2156200DOI
10.1111/j.1469-8986.2007.00594.xScopus ID
2-s2.0-36849092393 (requires institutional sign-in at Scopus site) 112 CitationsAbstract
Incentive delay tasks implicate the striatum and medial frontal cortex in reward processing. However, prior studies delivered more rewards than penalties, possibly leading to unwanted differences in signal-to-noise ratio. Also, whether particular brain regions are specifically involved in anticipation or consumption is unclear. We used a task featuring balanced incentive delivery and an analytic strategy designed to identify activity specific to anticipation or consumption. Reaction time data in two independent samples (n=13 and n=8) confirmed motivated responding. Functional magnetic resonance imaging revealed regions activated by anticipation (anterior cingulate) versus consumption (orbital and medial frontal cortex). Ventral striatum was active during reward anticipation but not significantly more so than during consumption. Although the study features several methodological improvements and helps clarify the neural basis of incentive processing, replications in larger samples are needed.
Author List
Dillon DG, Holmes AJ, Jahn AL, Bogdan R, Wald LL, Pizzagalli DAAuthor
Allison L. Jahn PhD Assistant Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultBrain
Consummatory Behavior
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Motivation
Psychomotor Performance
Reaction Time
Reward