Electro-oculography in autosomal dominant vitreoretinochoroidopathy. Arch Ophthalmol 1992 Nov;110(11):1563-7
Date
11/01/1992Pubmed ID
1444912DOI
10.1001/archopht.1992.01080230063021Scopus ID
2-s2.0-0026482971 (requires institutional sign-in at Scopus site) 33 CitationsAbstract
Thirteen members of a family presumed to be harboring the gene for autosomal dominant vitreoretinochoroidopathy were examined. In four affected members, electro-oculography demonstrated marked reduction of the Arden ratio (range, 1.1 to 1.5; normal, > or = 1.8), despite electroretinographic evidence of mildly affected rod function and normal cone function. These findings suggested that a diffuse disturbance of the photoreceptor-pigment epithelium complex may have been present prior to wide-spread loss of photoreceptor function in the affected members of this family. As in previously described families, the pattern of inheritance appeared consistent with autosomal dominance.
Author List
Han DP, Lewandowski MFAuthor
Dennis Han MD Emeritus Professor in the Ophthalmology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultChoroid Diseases
Dark Adaptation
Electrooculography
Electroretinography
Eye Diseases
Female
Fluorescein Angiography
Fundus Oculi
Humans
Light
Male
Middle Aged
Pedigree
Retinal Diseases
Retinitis Pigmentosa
Vitreous Body
