Sporadic Creutzfeldt-Jakob disease presenting as nonconvulsive status epilepticus case report and review of the literature. Clin Neurol Neurosurg 2010 Jul;112(6):537-40
Date
05/01/2010Pubmed ID
20430517DOI
10.1016/j.clineuro.2010.03.025Scopus ID
2-s2.0-77952887690 (requires institutional sign-in at Scopus site) 37 CitationsAbstract
Creutzfeldt-Jakob disease (CJD) is the most common transmissible human spongiform encephalopathy. Seizures and status epilepticus (SE) are an uncommon finding in CJD. We report a 64-year-old woman with rapid cognitive decline who had electroencephalographic (EEG) changes suggestive of nonconvulsive status epilepticus (NCSE). She was later diagnosed with sporadic CJD (sCJD). We also reviewed the literature for published cases on this topic. MEDLINE was employed to identify all published reports of CJD and SE. We identified 8 references with a total of 12 cases with CJD and NCSE. sCJD should be considered in the differential diagnosis of any patient who presents with rapid cognitive decline and EEG changes consistent with status epilepticus.
Author List
Espinosa PS, Bensalem-Owen MK, Fee DBAuthor
Dominic B. Fee MD Vice Chair, Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAged
Anxiety Disorders
Creutzfeldt-Jakob Syndrome
Electroencephalography
Female
Humans
Hypertension
Magnetic Resonance Imaging
Male
Middle Aged
Status Epilepticus
Urinary Tract Infections
