Langerhans' cell histiocytosis of the thymus associated with multilocular thymic cyst. Hum Pathol 2000 Dec;31(12):1532-5
Date
01/11/2001Pubmed ID
11150381DOI
10.1053/hupa.2000.20410Scopus ID
2-s2.0-0034526136 (requires institutional sign-in at Scopus site) 23 CitationsAbstract
Though Langerhans' cells are a normal component of the thymus, the pathologic entity of Langerhans' cell histiocytosis (LCH) occurs very uncommonly in this organ. The few reports of thymic LCH are nearly all in children or young adults and may or may not be associated with extrathymic clinical disease. Although radiographic descriptions of cyst formation in the thymus in association with LCH have been reported, no examples to our knowledge of thymic LCH have been reported in association with multilocular thymic cyst (MTC). We report a case of thymic LCH in association with an asymptomatic multilocular thymic cyst which was discovered as part of cardiothoracic surgery in a middle-aged man. To our knowledge, this is the first example of MTC occurring in association with thymic LCH. HUM PATHOL 31:1532-1535.
Author List
Wakely P Jr, Suster SMESH terms used to index this publication - Major topics in bold
BiomarkersFatal Outcome
Histiocytosis, Langerhans-Cell
Humans
Immunophenotyping
Male
Mediastinal Cyst
Middle Aged
Thymus Gland