Evaluation of an automatic method of measuring features of motor unit action potentials. Muscle Nerve 1989 Feb;12(2):141-8
Date
02/01/1989Pubmed ID
2710146DOI
10.1002/mus.880120209Scopus ID
2-s2.0-0024589171 (requires institutional sign-in at Scopus site) 97 CitationsAbstract
This study was performed to evaluate an automatic method of motor unit action potential (MUAP) analysis developed in our laboratory. MUAPs were recorded from the biceps brachii muscle of 68 normal subjects and 122 patients with nerve or muscle disease. The values of mean MUAP durations from normal subjects obtained by automatic analysis were similar to those reported in the literature. However, the normal range of MUAP amplitude and the incidence of polyphasic MUAPs were much higher. Normal ranges of mean MUAP area, area/amplitude ratio, and the number of turns were also defined. Automatic analysis demonstrated an abnormality of at least one MUAP feature in 70% of patients. There was concordance between automated analysis and visual assessment of MUAPs in 76% of patients with neuropathy but in only 50% of patients with myopathy. The relationships between different MUAP features seen in neuropathy and myopathy are explained in physiologic terms.
Author List
Stewart CR, Nandedkar SD, Massey JM, Gilchrist JM, Barkhaus PE, Sanders DBAuthor
Paul E. Barkhaus MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Action PotentialsAdolescent
Adult
Aged
Arm
Electromyography
Evaluation Studies as Topic
Humans
Middle Aged
Motor Neurons
Movement
Muscles
Muscular Diseases
Nervous System Diseases
