Primary sarcomas of the lung. Semin Diagn Pathol 1995 May;12(2):140-57
Date
05/01/1995Pubmed ID
7638447Scopus ID
2-s2.0-0029023235 (requires institutional sign-in at Scopus site) 67 CitationsAbstract
Primary pulmonary sarcomas are rare tumors. Because the lung is one of the favored metastatic sites for soft tissue sarcomas, care must be taken when evaluating these lesions to rule out the possibility of an alternate primary source by means of thorough clinical history and radiographic evaluation. In addition to the difficulties involved in separating primary from metastatic tumors, pulmonary sarcomas must be distinguished from a number of sarcomalike primary lung neoplasms, including spindle and giant cell (pleomorphic) carcinoma, and from mixed epithelial/mesenchymal lesions such as pulmonary blastoma and carcinosarcoma. The criteria helpful for accomplishing this distinction are discussed, along with a review of primary sarcomas of the lung, with emphasis on clinicopathologic, immunohistochemical, and ultrastructural features that may be of aid for diagnosis. Additionally, recent or newly described entities are also discussed, and evolving concepts on the pathogenesis and terminology of these lesions are underscored.
Author List
Suster SMESH terms used to index this publication - Major topics in bold
HamartomaHemangioendothelioma, Epithelioid
Humans
Lung Neoplasms
Mesenchymoma
Sarcoma
Sarcoma, Kaposi