Giant-cell neoplasm of the sphenoid sinus. Mt Sinai J Med 1989 Mar;56(2):118-22
Date
03/01/1989Pubmed ID
2546066Scopus ID
2-s2.0-0024560772 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
A rapidly growing giant-cell neoplasm arising in the sphenoid sinus of a 26-year-old man is reported. The patient's only initial symptoms were severe headaches and left sixth-nerve palsy. Computerized tomography of the brain showed extensive tumor infiltration of the bony structures and soft tissues of the base of the skull. A transsphenoidal surgical procedure proved unsuccessful in removing the tumor. Histologic examination revealed a proliferation of osteoclast-type giant cells against a background of highly atypical mononuclear cells, raising the question of malignancy. The differential diagnosis and problems in nomenclature of this lesion are discussed.
Author List
Suster S, Porges R, Tobias J, Nanes MMESH terms used to index this publication - Major topics in bold
AdultDiagnosis, Differential
Giant Cell Tumors
Histiocytoma, Benign Fibrous
Humans
Male
Paranasal Sinus Neoplasms
Sphenoid Sinus