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Neonatal outcomes in twin pregnancies complicated by gestational diabetes compared with non-diabetic twins. J Perinatol 2015 Dec;35(12):1043-7



Pubmed ID




Scopus ID

2-s2.0-84948082121   8 Citations


OBJECTIVE: To compare neonatal outcomes of twin pregnancies with gestational diabetes (GDM) and preexisting diabetes with non-diabetic twin pregnancies.

STUDY DESIGN: US birth data from 2006 to 2009 was used to compare twin pregnancies of 16 562 GDM and 2137 preexisting diabetic with 258 857 non-diabetic twin gestations. Adjusted odds ratios (aORs) were calculated to assess effects of GDM and preexisting diabetes on neonatal outcomes.

RESULT: Twin pregnancies with GDM vs non-diabetic twin pregnancies demonstrated decreased 5-min Apgar scores <4 (aOR 0.8, 95% confidence interval (CI) 0.68-0.94), fewer births before 32 weeks gestation (aOR 0.72, 95% CI 0.68-0.76), decreased birth weight less than the tenth percentile (aOR 0.84, 95% CI 0.81-0.89) and fifth percentile (aOR 0.85, 95% CI 0.81-0.89) and a trend toward lower rates of neonatal death (aOR 0.84, 95% CI 0.68-1.02).

CONCLUSION: Certain adverse outcomes in pregnancies with GDM may be attenuated in twin gestations; however, further investigation is warranted.

Author List

Foeller ME, Zhao S, Szabo A, Cruz MO


Meredith Cruz MD Associate Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin
Aniko Szabo PhD Professor in the Institute for Health and Equity department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Apgar Score
Diabetes, Gestational
Gestational Age
Infant, Newborn
Perinatal Death
Pregnancy Complications
Pregnancy in Diabetics
Pregnancy, Twin
Retrospective Studies
Young Adult
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a