Unraveling the transcriptional network controlling ES cell pluripotency. Genome Biol 2006;7(8):230
Date
09/01/2006Pubmed ID
16942632Pubmed Central ID
PMC1779601DOI
10.1186/gb-2006-7-8-230Scopus ID
2-s2.0-33845562043 (requires institutional sign-in at Scopus site) 35 CitationsAbstract
Embryonic stem cells (ES cells) are powerful tools for genetic engineering and hold significant potential for regenerative medicine. Recent work provides new insights into ES cell pluripotency and delineates separate transcriptional pathways in ES cells for maintenance of the undifferentiated state and for self-renewal.
Author List
Rao S, Orkin SHAuthor
Sridhar Rao MD, PhD Associate Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsCell Differentiation
Embryonic Stem Cells
Humans
Leukemia Inhibitory Factor
Mice
Octamer Transcription Factor-3
Pluripotent Stem Cells
RNA Interference
STAT Transcription Factors
Signal Transduction