Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission. Arch Intern Med 1983 May;143(5):1040-2
Date
05/01/1983Pubmed ID
6089681DOI
10.1001/archinte.1983.00350050206041Scopus ID
2-s2.0-84948725194 (requires institutional sign-in at Scopus site) 30 CitationsAbstract
A 40-year-old woman had visual loss and a large nonfunctioning pituitary tumor. After partial surgical resection and radiation treatment, clinical and biochemical evidence of Cushing's disease developed. The pituitary source of her adrenocorticotropic hormone hypersecretion was documented on selective venous sampling. After 18 months of medical therapy with metyrapone and aminoglutethimide, the patient experienced a spontaneous remission of her hypercortisolism. A "nonfunctioning" pituitary tumor has a hypersecretory potential.
Author List
Gogel EL, Salber PR, Tyrrell JB, Rosenblum ML, Findling JWAuthor
James W. Findling MD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Adenoma, ChromophobeAdrenocorticotropic Hormone
Adult
Aminoglutethimide
Cushing Syndrome
Female
Humans
Metyrapone
Pituitary Function Tests
Pituitary Neoplasms