Medical College of Wisconsin
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New insights into the versatile roles of platelet FlnA. Platelets 2013;24(1):1-5

Date

03/01/2012

Pubmed ID

22372530

Pubmed Central ID

PMC6781629

DOI

10.3109/09537104.2011.654004

Scopus ID

2-s2.0-84871764376 (requires institutional sign-in at Scopus site)   26 Citations

Abstract

Recent findings have identified critical roles for the actin filament-crosslinking protein filamin A (FlnA) in platelets and megakaryocytes. This short review focuses on the structure of FlnA and its interaction with the Von Willebrand Factor receptor GPIb-IX-V complex and the fibrinogen receptor, the integrin αIIbβ3 in platelets.

Author List

Falet H

Author

Herve Falet PhD Associate Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Blood Platelets
Carrier Proteins
Contractile Proteins
Filamins
Humans
Microfilament Proteins
Mutation
Protein Binding
Thrombocytopenia