Differentiating Familial Neuropathies from Guillain-Barré Syndrome. Pediatr Clin North Am 2017 Feb;64(1):231-252
Date
11/30/2016Pubmed ID
27894447DOI
10.1016/j.pcl.2016.08.015Scopus ID
2-s2.0-84998865507 (requires institutional sign-in at Scopus site) 3 CitationsAbstract
Differentiating Guillain-Barré syndrome (GBS) from inherited neuropathies and other acquired peripheral neuropathies requires understanding the atypical presentations of GBS and its variant forms, as well as historical and physical features suggestive of inherited neuropathies. GBS is typically characterized by the acute onset of ascending flaccid paralysis, areflexia, and dysesthesia secondary to peripheral nerve fiber demyelination. The disorder usually arises following a benign gastrointestinal or respiratory illness, is monophasic, reaches a nadir with several weeks, and responds to immunomodulatory therapy. Inherited neuropathies with onset before adulthood, whose presentation may mimic Guillain-Barré syndrome, are reviewed.
Author List
Bordini BJ, Monrad PAuthor
Brett J. Bordini MD Associate Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ChildDiagnosis, Differential
Guillain-Barre Syndrome
Humans
Immunomodulation
Immunotherapy
Peripheral Nervous System Diseases