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Endoscopic transnasal skull base surgery: pushing the boundaries. J Neurooncol 2016 Nov;130(2):319-330

Date

11/03/2016

Pubmed ID

27766473

DOI

10.1007/s11060-016-2274-y

Scopus ID

2-s2.0-84991753310 (requires institutional sign-in at Scopus site)   42 Citations

Abstract

The endoscopic endonasal approach (EEA) has significantly evolved since its initial uses in pituitary and sinonasal surgery. The literature is filled with reports and case series demonstrating efficacy and advantages for the entire ventral skull base. With competence in 'minimally invasive' parasellar approaches, larger and more complex approaches were developed to utilize the endonasal corridor to create maximally invasive endoscopic skull base procedures. The challenges of these more complex endoscopic procedures include a long learning curve and navigating in a narrow corridor; reconstruction of defects presented new challenges and early experience revealed a significantly higher risk of cerebrospinal fluid leak. Despite these challenges, there are many benefits to the EEA including avoidance of brain and neurovascular retraction, improved visualization, a direct corridor onto many tumors and the two-surgeon approach. Most importantly, the EEA provides a midline corridor to directly access tumors, which displace critical neurovascular structures laterally, giving it an inherent advantage of minimizing any manipulation of these structures and thus decreasing their potential injury.

Author List

Zwagerman NT, Zenonos G, Lieber S, Wang WH, Wang EW, Fernandez-Miranda JC, Snyderman CH, Gardner PA

Author

Nathan Zwagerman MD Associate Professor in the Neurosurgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Humans
Natural Orifice Endoscopic Surgery
Neuronavigation
Neurosurgical Procedures
Skull Base
Skull Base Neoplasms