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Prognostic factors in pediatric Hodgkin disease. Curr Oncol Rep 2003 Nov;5(6):498-504

Date

10/03/2003

Pubmed ID

14521809

DOI

10.1007/s11912-003-0011-0

Scopus ID

2-s2.0-2442482680   14 Citations

Abstract

The sensitivity of pediatric Hodgkin disease to radiation and chemotherapy has resulted in cure for most children and adolescents who have been diagnosed in the past three decades. Identification of prognostic factors in clinical trials has allowed for tailoring of therapeutic approaches to improve outcome in sequential trials. Tumor burden, symptoms, clinical features, pathology, response to therapy, biology, and host factors are reviewed in this context. New developments should be directed toward identification of factors associated with biologic mechanisms of disease to facilitate the development of biologically targeted therapies that will be more efficacious and less toxic.

Author List

Schwartz CL

Author

Cindy L. Schwartz MD, MPH Chief, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Hodgkin Disease
Humans
Prognosis
Risk Factors
jenkins-FCD Prod-461 7d7c6113fc1a2757d2947d29fae5861c878125ab