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Current Use and Trends in Hematopoietic Cell Transplantation in the United States. Biol Blood Marrow Transplant 2017 Sep;23(9):1417-1421

Date

06/14/2017

Pubmed ID

28606646

Pubmed Central ID

PMC5565685

DOI

10.1016/j.bbmt.2017.05.035

Scopus ID

2-s2.0-85023159496   96 Citations

Abstract

Hematopoietic Cell Transplantation (HCT) is an established curative treatment for a number of malignant and nonmalignant diseases involving the hematopoietic system and some solid tumors. In this report, we provide information about the number of HCT procedures performed in the United States in 2015, and analyze trends and outcomes of HCT as reported to the Center for International Blood and Marrow Transplant Research (CIBMTR). We show that the number of HCTs performed annually continues to increase, as the indications for HCT, preferred donor sources, and graft-versus-host prophylaxis continue to evolve. We report on general overall survival by indication, by disease status at transplantation, and by transplant type. This report provides a current perspective on transplantation activity in the United States with a focus on recent trends in alternative donors and contemporary transplantation practices.

Author List

D'Souza A, Lee S, Zhu X, Pasquini M

Authors

Anita D'Souza MD Associate Professor in the Medicine department at Medical College of Wisconsin
Marcelo C. Pasquini MD, MS Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Alemtuzumab
Antilymphocyte Serum
Calcineurin Inhibitors
Child
Graft vs Host Disease
Hematologic Neoplasms
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Histocompatibility Testing
Humans
Methotrexate
Myeloablative Agonists
Survival Analysis
Tissue Donors
Transplantation Conditioning
Transplantation, Autologous
Transplantation, Homologous
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a