Efficacy of a Weight Loss Intervention for African American Breast Cancer Survivors. J Clin Oncol 2017 Aug 20;35(24):2820-2828
Date
06/20/2017Pubmed ID
28628363Pubmed Central ID
PMC5562172DOI
10.1200/JCO.2016.71.9856Scopus ID
2-s2.0-85028582392 (requires institutional sign-in at Scopus site) 43 CitationsAbstract
Purpose African American women with breast cancer have higher cancer-specific and overall mortality rates. Obesity is common among African American women and contributes to breast cancer progression and numerous chronic conditions. Weight loss interventions among breast cancer survivors positively affect weight, behavior, biomarkers, and psychosocial outcomes, yet few target African Americans. This article examines the effects of Moving Forward, a weight loss intervention for African American breast cancer survivors (AABCS) on weight, body composition, and behavior. Patients and Methods Early-stage (I-III) AABCS were randomly assigned to a 6-month interventionist-guided (n = 125) or self-guided (n = 121) weight loss program supporting behavioral changes to promote a 5% weight loss. Anthropometric, body composition, and behavioral data were collected at baseline, postintervention (6 months), and follow-up (12 months). Descriptive statistics and mixed models analyses assessed differences between groups over time. Results Mean (± standard deviation) age, and body mass index were 57.5 (± 10.1) years and 36.1 (± 6.2) kg/m2, respectively, and 82% had stage I or II breast cancer. Both groups lost weight. Mean and percentage of weight loss were greater in the guided versus self-guided group (at 6 months: 3.5 kg v 1.3kg; P < .001; 3.6% v 1.4%; P < .001, respectively; at 12 months: 2.7 kg v 1.6 kg; P < .05; 2.6% v 1.6%; P < .05, respectively); 44% in the guided group and 19% in the self-guided group met the 5% goal. Body composition and behavioral changes were also greater in the interventionist-guided group at both time points. Conclusion The study supports the efficacy of a community-based interventionist-guided weight loss program targeting AABCS. Although mean weight loss did not reach the targeted 5%, the mean loss of > 3% at 6 months is associated with improved health outcomes. Affordable, accessible health promotion programs represent a critical resource for AABCS.
Author List
Stolley M, Sheean P, Gerber B, Arroyo C, Schiffer L, Banerjee A, Visotcky A, Fantuzzi G, Strahan D, Matthews L, Dakers R, Carridine-Andrews C, Seligman K, Springfield S, Odoms-Young A, Hong S, Hoskins K, Kaklamani V, Sharp LAuthors
Anjishnu Banerjee PhD Associate Professor in the Data Science Institute department at Medical College of WisconsinMelinda Stolley PhD Center Associate Director, Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Breast NeoplasmsFemale
Health Behavior
Humans
Middle Aged
Neoplasm Staging
Obesity
Survivors
Weight Reduction Programs