Radiological diagnosis of drop metastases from paediatric brain tumours using combination of 2D and 3D MRI sequences. Clin Radiol 2017 Oct;72(10):902.e13-902.e19
Date
05/27/2017Pubmed ID
28545686DOI
10.1016/j.crad.2017.04.016Scopus ID
2-s2.0-85019937101 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
AIM: To evaluate spinal magnetic resonance imaging (MRI) examinations using a combination of two-dimensional (2D) and three-dimensional (3D) MRI sequences for diagnosis of drop metastases.
MATERIALS AND METHODS: Fifty-five paediatric patients with primary brain tumours were evaluated for drop metastases at initial presentation using spinal MRI including sagittal 2D T1-weighted (W) contrast-enhanced (+C), axial 3D T1W+C volumetric interpolated breath-hold (VIBE), and sagittal 3D T2W SPACE (Sampling Perfection with Application optimised Contrasts using different flip angle Evolutions).
RESULTS: The MRI false-negative rate was 4%, and cerebrospinal fluid (CSF) false-negative rate was 16% (p=0.07). The 3D T1W+C VIBE increased the number of drop metastases detected in 42% of patients. Drop metastases were more conspicuous in 25% of patients on 3D T2W SPACE.
CONCLUSION: Spinal MRI examinations including 2D and 3D sequences demonstrate characteristics that may improve radiological diagnosis of drop metastases.
Author List
Kralik SF, O'Neill DP, Kamer AP, Rodriguez E, Ho CYAuthor
Darren P. O'Neill MD Interim Chair, Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentBrain Neoplasms
Child
Child, Preschool
Female
Humans
Imaging, Three-Dimensional
Infant
Magnetic Resonance Imaging
Male
Meningeal Neoplasms
Retrospective Studies
