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The Xenopus oocyte: a single-cell model for studying Ca2+ signaling. Cold Spring Harb Protoc 2013 Mar 01;2013(3)

Date

03/05/2013

Pubmed ID

23457336

Pubmed Central ID

PMC4017334

DOI

10.1101/pdb.top066308

Scopus ID

2-s2.0-84874704380   11 Citations

Abstract

In the four decades since the Xenopus oocyte was first demonstrated to have the capacity to translate exogenous mRNAs, this system has been exploited for many different experimental purposes. Typically, the oocyte is used either as a "biological test tube" for heterologous expression of proteins without any particular cell biological insight or, alternatively, it is used for applications where cell biology is paramount, such as investigations of the cellular adaptations that power early development. In this article, we discuss the utility of the Xenopus oocyte for studying Ca(2+) signaling in both these contexts.

Author List

Lin-Moshier Y, Marchant JS

Author

Jonathan S. Marchant PhD Chair, Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Calcium
Cytological Techniques
Oocytes
Signal Transduction
Xenopus
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a