Aqueous phase C-H bond oxidation reaction of arylalkanes catalyzed by a water-soluble cationic Ru(III) complex [(pymox-Me2)2RuCl2]+BF4-. Org Lett 2009 Apr 02;11(7):1567-9
Date
02/28/2009Pubmed ID
19245262Pubmed Central ID
PMC2667693DOI
10.1021/ol900097yScopus ID
2-s2.0-64349121535 (requires institutional sign-in at Scopus site) 87 CitationsAbstract
The cationic complex [(pymox-Me(2))RuCl(2)](+)BF(4)(-) was found to be a highly effective catalyst for the C-H bond oxidation reaction of arylalkanes in water. For example, the treatment of ethylbenzene (1.0 mmol) with t-BuOOH (3.0 mmol) and 1.0 mol % of the Ru catalyst in water (3 mL) cleanly produced PhCOCH(3) at room temperature. Both a large kinetic isotope effect (k(H)/k(D) = 14) and a relatively large Hammett value (rho = -1.1) suggest a solvent-caged oxygen rebounding mechanism via a Ru(IV)-oxo intermediate species.
Author List
Yi CS, Kwon KH, Lee DWAuthor
Chae Yi PhD Professor, Inorganic and Organometallic Chemistry, Homogeneous Catalysis in the Chemistry department at Marquette UniversityMESH terms used to index this publication - Major topics in bold
AlkanesCatalysis
Combinatorial Chemistry Techniques
Kinetics
Molecular Structure
Organometallic Compounds
Oxidation-Reduction
Ruthenium
Water