Medical College of Wisconsin
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Real-time MR imaging of myocardial regional function using strain-encoding (SENC) with tissue through-plane motion tracking. J Magn Reson Imaging 2007 Dec;26(6):1461-70

Date

10/31/2007

Pubmed ID

17968902

DOI

10.1002/jmri.21125

Scopus ID

2-s2.0-37349015558   33 Citations

Abstract

PURPOSE: To implement real-time myocardial strain-encoding (SENC) imaging in combination with tracking the tissue displacement in the through-plane direction.

MATERIALS AND METHODS: SENC imaging was combined with the slice-following technique by implementing three-dimensional (3D) selective excitation. Certain adjustments were implemented to reduce scan time to one heartbeat. A total of 10 volunteers and five pigs were scanned on a 3T MRI scanner. Spatial modulation of magnetization (SPAMM)-tagged images were acquired on planes orthogonal to the SENC planes for comparison. Myocardial infarction (MI) was induced in two pigs and the resulting SENC images were compared to standard delayed-enhancement (DE) images.

RESULTS: The strain values computed from SENC imaging with slice-following showed significant difference from those acquired without slice-following, especially during systole (P < 0.01). The strain curves computed from the SENC images with and without slice-following were similar to those computed from the orthogonal SPAMM images, with and without, respectively, tracking the tag line displacement in the strain direction. The resulting SENC images showed good agreement with the DE images in identifying MI in infarcted pigs.

CONCLUSION: Correction of through-plane motion in real-time cardiac functional imaging is feasible using slice-following. The strain measurements are more accurate than conventional SENC measurements in humans and animals, as validated with conventional MRI tagging.

Author List

Ibrahim el-SH, Stuber M, Fahmy AS, Abd-Elmoniem KZ, Sasano T, Abraham MR, Osman NF

Author

El-Sayed H. Ibrahim PhD Associate Professor in the Radiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Humans
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Movement
Myocardial Contraction
Myocardial Infarction
Phantoms, Imaging
Swine