Combined functional and viability cardiac MR imaging in a single breathhold. Magn Reson Med 2007 Oct;58(4):843-9
Date
09/28/2007Pubmed ID
17899600DOI
10.1002/mrm.21390Scopus ID
2-s2.0-35048846481 (requires institutional sign-in at Scopus site) 22 CitationsAbstract
The combination of cardiac viability and functional information enhances the identification of different heart tissues in the setting of ischemic heart disease. A method has recently been proposed for obtaining black-blood delayed-enhancement (DE) viability images using the stimulated-echo acquisition mode (STEAM) MRI pulse sequence in a single short breathhold. The method was validated against conventional inversion-recovery (IR) DE images for identifying regions of myocardial infarction (MI). The method was based on the acquisition of three consecutive images of the same anatomical slice. One image has T(1)-weighted contrast in which infarction appears bright. The two other images are used to construct an anatomical image of the heart, which is combined with the first image to produce a black-blood viability image. However, using appropriate modulation and demodulation frequencies, the latter two images bear useful information about myocardial deformation that results in a cardiac strain-encoding (SENC) functional image. In this work, a method is proposed for obtaining three consecutive SENC images in a single acquisition that can be combined to produce a composite image of the heart, which shows both functional and viability information. The proposed technique reduces scan time by one-half, compared with separate acquisitions of functional and viability images, and alleviates misregistration problems caused by separate breathholds.
Author List
Ibrahim el-SH, Stuber M, Kraitchman DL, Weiss RG, Osman NFMESH terms used to index this publication - Major topics in bold
AnimalsCoronary Vessels
Dogs
Heart
Magnetic Resonance Imaging
Myocardial Infarction
Phantoms, Imaging
Tissue Survival
