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Mucins in protozoan parasites. Front Biosci 2001 Oct 01;6:D1276-83

Date

10/02/2001

Pubmed ID

11578964

DOI

10.2741/jain

Scopus ID

2-s2.0-0035486868 (requires institutional sign-in at Scopus site)   6 Citations

Abstract

Studies on host-pathogen interactions have led to the discovery of various cell surface associated and secretory molecules. Mucins and mucin-like molecules have recently been described in several protozoan parasites, at different stages of the life cycle. These share many structural and compositional features with mammalian mucins, but vary in several other aspects. It is now becoming evident that mucins in parasite are involved in cell-cell interaction and cell surface protection, thus helping the parasite to establish infection. A large number of mucin like genes from the parasite genome have been reported, and their expression differ during the developmental stages of the parasite. In this review, we describe the structure and functions of mucin and mucin-like molecules in parasitic protozoa.

Author List

Jain M, Karan D, Batra SK, Varshney GC



MESH terms used to index this publication - Major topics in bold

Animals
Eukaryota
Mucins
Protozoan Proteins