Congenital Disorders of Platelet Function and Number. Pediatr Clin North Am 2018 Jun;65(3):561-578
Date
05/29/2018Pubmed ID
29803283DOI
10.1016/j.pcl.2018.02.009Scopus ID
2-s2.0-85047384974 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
Mucocutaneous bleeding symptoms and/or persistent thrombocytopenia occur in individuals with congenital disorders of platelet function and number. Apart from bleeding, these disorders are often associated with additional hematologic and clinical manifestations, including auditory, immunologic, and oncologic disease. Autosomal recessive, dominant, and X-linked inheritance patterns have been demonstrated. Precise delineation of the molecular cause of the platelet disorder can aid the pediatrician in the detection and prevention of specific disorder-associated manifestations and guide appropriate treatment and anticipatory care for the patient and family.
Author List
Sharma R, Perez Botero J, Jobe SMAuthor
Juliana Perez Botero MD Assistant Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Blood Coagulation Disorders, InheritedBlood Platelet Disorders
Humans
Thrombocytopenia
