Faculty Collaboration Database

Low-grade endometrial stromal sarcoma presenting as multiple pulmonary nodules: A potential pitfall in fine needle aspiration and core biopsy specimens - A Cytological - Pathological Correlation. Ann Diagn Pathol 2018 Oct;36:38-43

Date

07/29/2018

Pubmed ID

30055523

DOI

10.1016/j.anndiagpath.2018.06.004

Scopus ID

2-s2.0-85050339286 (requires institutional sign-in at Scopus site)   6 Citations

Abstract

Low-grade endometrial stromal sarcoma (LGESS) is the second most common malignant mesenchymal tumor of the uterus. The most common location is the uterine corpus, but it can also primarily arise in a variety of extrauterine locations such as pelvis, ovary, abdominal cavity, vagina, and vulva. We are reporting a case of a 47-year-old female with no significant medical history who presented with multiple pulmonary nodules. Fine needle aspiration (FNA) specimen revealed spindle cell neoplasm consistent with the diagnosis of LGESS. The differential diagnosis included neuroendocrine tumor, synovial sarcoma, solitary fibrous tumor, smooth muscle tumors, and peripheral nerve sheath tumors. The clinical, cytological, and histopathologic details of this case, as well as a discussion of the potential pitfalls and differential diagnosis of spindle cell lesions of the lung are described.

Author List

Ronen S, Narula N, Koizumi JH, Hunt B, Giorgadze T

Author

Bryan C. Hunt MD Associate Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Biopsy, Fine-Needle
Diagnosis, Differential
Endometrial Neoplasms
Endometrial Stromal Tumors
Female
Humans
Middle Aged
Multiple Pulmonary Nodules
Neoplasm Grading
Sarcoma, Endometrial Stromal
Sarcoma, Synovial
Smooth Muscle Tumor