Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Differentiating tic-related from non-tic-related impairment in children with persistent tic disorders. Compr Psychiatry 2018 11;87:38-45



Pubmed ID


Pubmed Central ID




Scopus ID

2-s2.0-85052890213   6 Citations


Children with persistent (chronic) tic disorders (PTDs) experience impairment across multiple domains of functioning, but given high rates of other non-tic-related conditions, it is often difficult to differentiate the extent to which such impairment is related to tics or to other problems. The current study used the Child Tourette's Syndrome Impairment Scale - Parent Report (CTIM-P) to examine parents' attributions of their child's impairment in home, school, and social domains in a sample of 58 children with PTD. Each domain was rated on the extent to which the parents perceived that impairment was related to tics versus non-tic-related concerns. In addition, the Yale Global Tic Severity Scale (YGTSS) was used to explore the relationship between tic-related impairment and tic severity. Results showed impairment in school and social activities was not differentially attributed to tics versus non-tic-related impairment, but impairment in home activities was attributed more to non-tic-related concerns than tics themselves. Moreover, tic severity was significantly correlated with tic-related impairment in home, school, and social activities, and when the dimensions of tic severity were explored, impairment correlated most strongly with motor tic complexity. Results suggest that differentiating tic-related from non-tic-related impairment may be clinically beneficial and could lead to treatments that more effectively target problems experienced by children with PTDs.

Author List

Stiede JT, Alexander JR, Wellen B, Bauer CC, Himle MB, Mouton-Odum S, Woods DW


Jennifer Alexander in the CTSI department at Medical College of Wisconsin - CTSI

MESH terms used to index this publication - Major topics in bold

Diagnosis, Differential
Personality Disorders
Severity of Illness Index
Social Behavior
Social Perception
Tic Disorders
Tourette Syndrome