Catalytic Synthesis of Substituted Indoles and Quinolines from the Dehydrative C-H Coupling of Arylamines with 1,2- and 1,3-Diols. Organometallics 2016 Jun 13;35(11):1973-1977
Date
06/13/2016Pubmed ID
30505062Pubmed Central ID
PMC6261509DOI
10.1021/acs.organomet.6b00273Scopus ID
2-s2.0-84974784214 (requires institutional sign-in at Scopus site) 28 CitationsAbstract
The cationic ruthenium-hydride complex catalyzes dehydrative C-H coupling reaction of arylamines with 1,2-diols to form the indole products. The analogous coupling of arylamines with 1,3-diols afforded the substituted quinolines. The catalytic method directly forms these coupling products in a highly regioselective manner without generating any toxic byproducts.
