Neuroblastoma: Tumor Biology and Its Implications for Staging and Treatment. Children (Basel) 2019 Jan 17;6(1)
Date
01/20/2019Pubmed ID
30658459Pubmed Central ID
PMC6352222DOI
10.3390/children6010012Scopus ID
2-s2.0-85068987911 (requires institutional sign-in at Scopus site) 44 CitationsAbstract
Neuroblastoma, the most common extracranial solid tumor of childhood, has widely variable outcomes dependent on the specific biology of the tumor. In this review, current biologic principles that are used to stratify risk and guide treatment algorithms are discussed. The role for surgical resection in neuroblastoma is also reviewed, including the indications and timing of surgery within the greater treatment plan.
