Medical College of Wisconsin
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Publications indexed to the term Gain of Function Mutation

FacultyTitle
1RAS and RHO family GTPase mutations in cancer: twin sons of different mothers? (Hodge RG, Schaefer A, Howard SV, Der CJ) Crit Rev Biochem Mol Biol 2020 Aug;55(4):386-407       41 Citations
1Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer. (Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ) Cancer Discov 2020 Feb;10(2):288-305       151 Citations
1Gain of function in somatic TP53 mutations is associated with immune-rich breast tumors and changes in tumor-associated macrophages. (Behring M, Vazquez AI, Cui X, Irvin MR, Ojesina AI, Agarwal S, Manne U, Shrestha S) Mol Genet Genomic Med 2019 Dec;7(12):e1001       14 Citations