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Publications indexed to the term Cell Cycle

FacultyTitle
4Runx1 is sufficient but not required for cardiomyocyte cell-cycle activation. (Akins KA, Flinn MA, Swift SK, Chanjeevaram SV, Purdy AL, Buddell T, Kolell ME, Andresen KG, Paddock S, Buday SL, Veldman MB, O'Meara CC, Patterson M) Am J Physiol Heart Circ Physiol 2024 Aug 01;327(2):H377-H389       7 Citations
4Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry. (Pollin G, De Assuncao TM, Doria Jorge S, Chi YI, Charlesworth MC, Madden B, Iovanna J, Zimmermann MT, Urrutia R, Lomberk G) Biosci Rep 2023 Oct 31;43(10)       2 Citations
2Tnni3k influences cardiomyocyte S-phase activity and proliferation. (Purdy AL, Swift SK, Sucov HM, Patterson M) J Mol Cell Cardiol 2023 Oct;183:22-26       8 Citations
1The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state. (Fong BC, Chakroun I, Iqbal MA, Paul S, Bastasic J, O'Neil D, Yakubovich E, Bejjani AT, Ahmadi N, Carter A, Clark A, Leone G, Park DS, Ghanem N, Vandenbosch R, Slack RS) Cell Rep 2022 Nov 01;41(5):111578       16 Citations
2Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images. (Pécot T, Cuitiño MC, Johnson RH, Timmers C, Leone G) PLoS Comput Biol 2022 Mar;18(3):e1009949       10 Citations
5Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration. (Auchampach J, Han L, Huang GN, Kühn B, Lough JW, O'Meara CC, Payumo AY, Rosenthal NA, Sucov HM, Yutzey KE, Patterson M) Am J Physiol Heart Circ Physiol 2022 Apr 01;322(4):H579-H596       39 Citations
1Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. (Xie XP, Laks DR, Sun D, Ganbold M, Wang Z, Pedraza AM, Bale T, Tabar V, Brennan C, Zhou X, Parada LF) Dev Cell 2022 Jan 10;57(1):32-46.e8       152 Citations
2Crosstalk between Plk1, p53, cell cycle, and G2/M DNA damage checkpoint regulation in cancer: computational modeling and analysis. (Jung Y, Kraikivski P, Shafiekhani S, Terhune SS, Dash RK) NPJ Syst Biol Appl 2021 Dec 09;7(1):46       60 Citations
5Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction. (Wang X, Wan TC, Lauth A, Purdy AL, Kulik KR, Patterson M, Lough JW, Auchampach JA) J Mol Cell Cardiol 2022 Feb;163:9-19       16 Citations
3IL4Rα signaling promotes neonatal cardiac regeneration and cardiomyocyte cell cycle activity. (Paddock SJ, Swift SK, Alencar-Almeida V, Kenarsary A, Alvarez-Argote S, Flinn MA, Patterson M, O'Meara CC) J Mol Cell Cardiol 2021 Dec;161:62-74       21 Citations
2Myh6-driven Cre recombinase activates the DNA damage response and the cell cycle in the myocardium in the absence of loxP sites. (Wang X, Lauth A, Wan TC, Lough JW, Auchampach JA) Dis Model Mech 2020 Dec 18;13(12)       19 Citations
2Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition. (Roy S, Kapoor A, Zhu F, Mukhopadhyay R, Ghosh AK, Lee H, Mazzone J, Posner GH, Arav-Boger R) J Biol Chem 2020 Oct 30;295(44):15013-15028       18 Citations
3p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis. (Wang F, Qi XM, Wertz R, Mortensen M, Hagen C, Evans J, Sheinin Y, James M, Liu P, Tsai S, Thomas J, Mackinnon A, Dwinell M, Myers CR, Bartrons Bach R, Fu L, Chen G) Cancer Res 2020 Aug 15;80(16):3251-3264       72 Citations
1Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance. (Numata A, Kwok HS, Zhou QL, Li J, Tirado-Magallanes R, Angarica VE, Hannah R, Park J, Wang CQ, Krishnan V, Rajagopalan D, Zhang Y, Zhou S, Welner RS, Osato M, Jha S, Bohlander SK, Göttgens B, Yang H, Benoukraf T, Lough JW, Bararia D, Tenen DG) Blood 2020 Oct 08;136(15):1735-1747       33 Citations
2Network mechanisms and dysfunction within an integrated computational model of progression through mitosis in the human cell cycle. (Terhune SS, Jung Y, Cataldo KM, Dash RK) PLoS Comput Biol 2020 Apr;16(4):e1007733       8 Citations
1Differential Cytotoxicity Induced by Transition Metal Oxide Nanoparticles is a Function of Cell Killing and Suppression of Cell Proliferation. (Tolliver LM, Holl NJ, Hou FYS, Lee HJ, Cambre MH, Huang YW) Int J Mol Sci 2020 Mar 03;21(5)       23 Citations
2Comprehensive molecular characterization of mitochondrial genomes in human cancers. (Yuan Y, Ju YS, Kim Y, Li J, Wang Y, Yoon CJ, Yang Y, Martincorena I, Creighton CJ, Weinstein JN, Xu Y, Han L, Kim HL, Nakagawa H, Park K, Campbell PJ, Liang H, PCAWG Consortium) Nat Genet 2020 Mar;52(3):342-352       358 Citations
1Soluble CD137 Ameliorates Acute Type 1 Diabetes by Inducing T Cell Anergy. (Itoh A, Ortiz L, Kachapati K, Wu Y, Adams D, Bednar K, Mukherjee S, Chougnet C, Mittler RS, Chen YG, Dolan L, Ridgway WM) Front Immunol 2019;10:2566       24 Citations
1FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning. (Fulcher LJ, He Z, Mei L, Macartney TJ, Wood NT, Prescott AR, Whigham AJ, Varghese J, Gourlay R, Ball G, Clarke R, Campbell DG, Maxwell CA, Sapkota GP) EMBO Rep 2019 Sep;20(9):e47495       36 Citations
1Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. (Clijsters L, Hoencamp C, Calis JJA, Marzio A, Handgraaf SM, Cuitino MC, Rosenberg BR, Leone G, Pagano M) Mol Cell 2019 Jun 20;74(6):1264-1277.e7       97 Citations
1Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. (Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, Ostrowski MC, Pagano M, Leone G) Cell Rep 2019 Jun 18;27(12):3547-3560.e5       51 Citations
1Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma. (Luchtel RA, Zimmermann MT, Hu G, Dasari S, Jiang M, Oishi N, Jacobs HK, Zeng Y, Hundal T, Rech KL, Ketterling RP, Lee JH, Eckloff BW, Yan H, Gaonkar KS, Tian S, Ye Z, Kadin ME, Sidhu J, Jiang L, Voss J, Link BK, Syrbu SI, Facchetti F, Bennani NN, Slager SL, Ordog T, Kocher JP, Cerhan JR, Ansell SM, Feldman AL) Blood 2019 Jun 27;133(26):2776-2789       69 Citations
1Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity. (Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Lin CC, Huang SC, Lai CW, Cook ME, Taneja R, Stappenbeck TS, Randolph GJ, Artyomov MN, Urban JF Jr, Edelson BT) Nat Immunol 2019 Jun;20(6):687-700       68 Citations
4IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration. (Wodsedalek DJ, Paddock SJ, Wan TC, Auchampach JA, Kenarsary A, Tsaih SW, Flister MJ, O'Meara CC) Am J Physiol Heart Circ Physiol 2019 Jan 01;316(1):H24-H34       46 Citations
2Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin. (Murthy T, Bluemn T, Gupta AK, Reimer M Jr, Rao S, Pillai MM, Minella AC) J Biol Chem 2018 Jun 29;293(26):10220-10234       19 Citations
1Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. (Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, Liu J, Wu Y, Jin VX, Dai X, Guo J, Liu J, Jiang S, Li J, Asara JM, Brown M, Hung MC, Wei W) Mol Cell 2018 Jan 18;69(2):279-291.e5       169 Citations
1Inactivation of AMMECR1 is associated with growth, bone, and heart alterations. (Moysés-Oliveira M, Giannuzzi G, Fish RJ, Rosenfeld JA, Petit F, Soares MF, Kulikowski LD, Di-Battista A, Zamariolli M, Xia F, Liehr T, Kosyakova N, Carvalheira G, Parker M, Seaby EG, Ennis S, Gilbert RD, Hagelstrom RT, Cremona ML, Li WL, Malhotra A, Chandrasekhar A, Perry DL, Taft RJ, McCarrier J, Basel DG, Andrieux J, Stumpp T, Antunes F, Pereira GJ, Neerman-Arbez M, Meloni VA, Drummond-Borg M, Melaragno MI, Reymond A) Hum Mutat 2018 Feb;39(2):281-291       17 Citations
1Sphingolipid pathway enzymes modulate cell fate and immune responses. (Molino S, Tate E, McKillop WM, Medin JA) Immunotherapy 2017 Nov;9(14):1185-1198       29 Citations
1Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration. (Akan I, Olivier-Van Stichelen S, Bond MR, Hanover JA) J Neurochem 2018 Jan;144(1):7-34       69 Citations
1Analysis of the whole transcriptome from gingivo-buccal squamous cell carcinoma reveals deregulated immune landscape and suggests targets for immunotherapy. (Singh R, De Sarkar N, Sarkar S, Roy R, Chattopadhyay E, Ray A, Biswas NK, Maitra A, Roy B) PLoS One 2017;12(9):e0183606       6 Citations
4SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression. (Gonyo P, Bergom C, Brandt AC, Tsaih SW, Sun Y, Bigley TM, Lorimer EL, Terhune SS, Rui H, Flister MJ, Long RM, Williams CL) Oncogene 2017 Dec 14;36(50):6873-6883       13 Citations
1Vandetanib and cabozantinib potentiate mitochondria-targeted agents to suppress medullary thyroid carcinoma cells. (Starenki D, Hong SK, Wu PK, Park JI) Cancer Biol Ther 2017 Jul 03;18(7):473-483       19 Citations
3Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe. (Mathison A, Salmonson A, Missfeldt M, Bintz J, Williams M, Kossak S, Nair A, de Assuncao TM, Christensen T, Buttar N, Iovanna J, Huebert R, Lomberk G) Mol Cancer Res 2017 Aug;15(8):984-997       19 Citations
1Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer. (Rabinowicz N, Mangala LS, Brown KR, Checa-Rodriguez C, Castiel A, Moskovich O, Zarfati G, Trakhtenbrot L, Levy-Barda A, Jiang D, Rodriguez-Aguayo C, Pradeep S, van Praag Y, Lopez-Berestein G, David A, Novikov I, Huertas P, Rottapel R, Sood AK, Izraeli S) Oncotarget 2017 Apr 18;8(16):27380-27392       10 Citations
1FX11 inhibits aerobic glycolysis and growth of neuroblastoma cells. (Rellinger EJ, Craig BT, Alvarez AL, Dusek HL, Kim KW, Qiao J, Chung DH) Surgery 2017 Mar;161(3):747-752       56 Citations
1E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. (Swartz KL, Wood SN, Murthy T, Ramirez O, Qin G, Pillai MM, Rao S, Minella AC) Mol Cell Biol 2017 Jan 01;37(1)       27 Citations
5Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells. (Cheng G, Zielonka J, Ouari O, Lopez M, McAllister D, Boyle K, Barrios CS, Weber JJ, Johnson BD, Hardy M, Dwinell MB, Kalyanaraman B) Cancer Res 2016 Jul 01;76(13):3904-15       194 Citations
1Cell-Cycle Gene Alterations in 4,864 Tumors Analyzed by Next-Generation Sequencing: Implications for Targeted Therapeutics. (Helsten T, Kato S, Schwaederle M, Tomson BN, Buys TP, Elkin SK, Carter JL, Kurzrock R) Mol Cancer Ther 2016 Jul;15(7):1682-90       40 Citations
1Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities. (Pfaltzgraff ER, Roth GM, Miller PM, Gintzig AG, Ohi R, Bader DM) Mol Biol Cell 2016 Jul 01;27(13):1990-9       15 Citations
1Evolution of an ancient protein function involved in organized multicellularity in animals. (Anderson DP, Whitney DS, Hanson-Smith V, Woznica A, Campodonico-Burnett W, Volkman BF, King N, Thornton JW, Prehoda KE) Elife 2016 Jan 07;5:e10147       56 Citations
1The Spectrum of E2F in Liver Disease--Mediated Regulation in Biology and Cancer. (Huntington JT, Tang X, Kent LN, Schmidt CR, Leone G) J Cell Physiol 2016 Jul;231(7):1438-49       11 Citations
1MicroRNA in prostate cancer. (Khanmi K, Ignacimuthu S, Paulraj MG) Clin Chim Acta 2015 Dec 07;451(Pt B):154-60       36 Citations
1RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells. (Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D) J Cell Sci 2015 Oct 01;128(19):3556-68       40 Citations
1Inhibition of human cytomegalovirus replication by artemisinins: effects mediated through cell cycle modulation. (Roy S, He R, Kapoor A, Forman M, Mazzone JR, Posner GH, Arav-Boger R) Antimicrob Agents Chemother 2015 Jul;59(7):3870-9       34 Citations
1Active ERK2 is sufficient to mediate growth arrest and differentiation signaling. (Wu PK, Hong SK, Yoon SH, Park JI) FEBS J 2015 Mar;282(6):1017-30       21 Citations
1A full bayesian approach for boolean genetic network inference. (Han S, Wong RK, Lee TC, Shen L, Li SY, Fan X) PLoS One 2014;9(12):e115806       17 Citations
1A systematic analysis of neonatal mouse heart regeneration after apical resection. (Bryant DM, O'Meara CC, Ho NN, Gannon J, Cai L, Lee RT) J Mol Cell Cardiol 2015 Feb;79:315-8       95 Citations
1Transcriptional reversion of cardiac myocyte fate during mammalian cardiac regeneration. (O'Meara CC, Wamstad JA, Gladstone RA, Fomovsky GM, Butty VL, Shrikumar A, Gannon JB, Boyer LA, Lee RT) Circ Res 2015 Feb 27;116(5):804-15       138 Citations
1Gene Ontology Consortium: going forward. (Gene Ontology Consortium) Nucleic Acids Res 2015 Jan;43(Database issue):D1049-56       2883 Citations
1Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function. (Pan J, Zhang Q, Liu Q, Komas SM, Kalyanaraman B, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2014 Nov;7(11):1149-59       41 Citations
1Forkhead box M1 regulates quiescence-associated radioresistance of human head and neck squamous carcinoma cells. (Eckers JC, Kalen AL, Sarsour EH, Tompkins VS, Janz S, Son JM, Doskey CM, Buettner GR, Goswami PC) Radiat Res 2014 Oct;182(4):420-9       23 Citations
1Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed. (Patki M, Gadgeel S, Huang Y, McFall T, Shields AF, Matherly LH, Bepler G, Ratnam M) J Thorac Oncol 2014 Apr;9(4):519-26       29 Citations
1SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers. (Schuld NJ, Hauser AD, Gastonguay AJ, Wilson JM, Lorimer EL, Williams CL) Cell Cycle 2014;13(6):941-52       19 Citations
1Sperm associated antigen 9 plays an important role in bladder transitional cell carcinoma. (Kanojia D, Garg M, Saini S, Agarwal S, Parashar D, Jagadish N, Seth A, Bhatnagar A, Gupta A, Kumar R, Lohiya NK, Suri A) PLoS One 2013;8(12):e81348       36 Citations
1α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. (Sengupta S, Weeraratne SD, Sun H, Phallen J, Rallapalli SK, Teider N, Kosaras B, Amani V, Pierre-Francois J, Tang Y, Nguyen B, Yu F, Schubert S, Balansay B, Mathios D, Lechpammer M, Archer TC, Tran P, Reimer RJ, Cook JM, Lim M, Jensen FE, Pomeroy SL, Cho YJ) Acta Neuropathol 2014 Apr;127(4):593-603       55 Citations
1Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. (Francis JM, Kiezun A, Ramos AH, Serra S, Pedamallu CS, Qian ZR, Banck MS, Kanwar R, Kulkarni AA, Karpathakis A, Manzo V, Contractor T, Philips J, Nickerson E, Pho N, Hooshmand SM, Brais LK, Lawrence MS, Pugh T, McKenna A, Sivachenko A, Cibulskis K, Carter SL, Ojesina AI, Freeman S, Jones RT, Voet D, Saksena G, Auclair D, Onofrio R, Shefler E, Sougnez C, Grimsby J, Green L, Lennon N, Meyer T, Caplin M, Chung DC, Beutler AS, Ogino S, Thirlwell C, Shivdasani R, Asa SL, Harris CR, Getz G, Kulke M, Meyerson M) Nat Genet 2013 Dec;45(12):1483-6       296 Citations
1NOTCH3 is a prognostic factor that promotes glioma cell proliferation, migration and invasion via activation of CCND1 and EGFR. (Alqudah MA, Agarwal S, Al-Keilani MS, Sibenaller ZA, Ryken TC, Assem M) PLoS One 2013;8(10):e77299       52 Citations
1Targeting SRC and tubulin in mucinous ovarian carcinoma. (Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK) Clin Cancer Res 2013 Dec 01;19(23):6532-43       37 Citations
1Pro-survival and pro-growth effects of stress-induced nitric oxide in a prostate cancer photodynamic therapy model. (Bhowmick R, Girotti AW) Cancer Lett 2014 Feb 01;343(1):115-22       64 Citations
1Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. (Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB) Am J Physiol Endocrinol Metab 2013 Sep 01;305(5):E600-10       41 Citations
1Endocrine resistance: what do we know? (Miller TW) Am Soc Clin Oncol Educ Book 2013       19 Citations
1A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal. (Janku F, Huang HJ, Angelo LS, Kurzrock R) Oncotarget 2013 Mar;4(3):463-73       31 Citations
1Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. (Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS) Cell Stem Cell 2013 Apr 04;12(4):440-52       75 Citations
1Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. (Tong L, Png E, Aihua H, Yong SS, Yeo HL, Riau A, Mendoz E, Chaurasia SS, Lim CT, Yiu TW, Iismaa SE) Biochim Biophys Acta 2013 Jun;1833(6):1304-15       25 Citations
1Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection. (Savaryn JP, Reitsma JM, Bigley TM, Halligan BD, Qian Z, Yu D, Terhune SS) J Virol 2013 Mar;87(5):2463-74       29 Citations
4Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. (Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr) Hypertension 2013 Jan;61(1):208-15       18 Citations
1Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling. (Lin-Moshier Y, Sebastian PJ, Higgins L, Sampson ND, Hewitt JE, Marchant JS) J Biol Chem 2013 Jan 04;288(1):355-67       78 Citations
2Canonical and atypical E2Fs regulate the mammalian endocycle. (Chen HZ, Ouseph MM, Li J, Pécot T, Chokshi V, Kent L, Bae S, Byrne M, Duran C, Comstock G, Trikha P, Mair M, Senapati S, Martin CK, Gandhi S, Wilson N, Liu B, Huang YW, Thompson JC, Raman S, Singh S, Leone M, Machiraju R, Huang K, Mo X, Fernandez S, Kalaszczynska I, Wolgemuth DJ, Sicinski P, Huang T, Jin V, Leone G) Nat Cell Biol 2012 Nov;14(11):1192-202       140 Citations
1Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling. (Pulikkan JA, Madera D, Xue L, Bradley P, Landrette SF, Kuo YH, Abbas S, Zhu LJ, Valk P, Castilla LH) Blood 2012 Jul 26;120(4):868-79       48 Citations
1The role of Rac1 in the regulation of NF-κB activity, cell proliferation, and cell migration in non-small cell lung carcinoma. (Gastonguay A, Berg T, Hauser AD, Schuld N, Lorimer E, Williams CL) Cancer Biol Ther 2012 Jun;13(8):647-56       94 Citations
3Stress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytes. (Fisher JB, Kim MS, Blinka S, Ge ZD, Wan T, Duris C, Christian D, Twaroski K, North P, Auchampach J, Lough J) PLoS One 2012;7(2):e31569       18 Citations
1Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants. (Sapetto-Rebow B, McLoughlin SC, O'Shea LC, O'Leary O, Willer JR, Alvarez Y, Collery R, O'Sullivan J, Van Eeden F, Hensey C, Kennedy BN) BMC Dev Biol 2011 Nov 23;11:71       19 Citations
1Integrative identification of core genetic regulatory modules via a structural model-based clustering method. (Tang B, Chen SS, Jin VX) Int J Comput Biol Drug Des 2011;4(2):127-46       2 Citations
1Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest. (Reitsma JM, Savaryn JP, Faust K, Sato H, Halligan BD, Terhune SS) Cell Host Microbe 2011 Feb 17;9(2):103-14       65 Citations
1Global analysis of phase locking in gene expression during cell cycle: the potential in network modeling. (Gao S, Hartman JL 4th, Carter JL, Hessner MJ, Wang X) BMC Syst Biol 2010 Dec 03;4:167       10 Citations
1C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations. (Pulikkan JA, Peramangalam PS, Dengler V, Ho PA, Preudhomme C, Meshinchi S, Christopeit M, Nibourel O, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G) Blood 2010 Dec 16;116(25):5638-49       129 Citations
1Acute and chronic radiation injury. (Brown KR, Rzucidlo E) J Vasc Surg 2011 Jan;53(1 Suppl):15S-21S       189 Citations
1The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. (Yang X, Lu X, Lombès M, Rha GB, Chi YI, Guerin TM, Smart EJ, Liu J) Cell Metab 2010 Mar 03;11(3):194-205       435 Citations
1Pterostilbene inhibits pancreatic cancer in vitro. (Mannal PW, Alosi JA, Schneider JG, McDonald DE, McFadden DW) J Gastrointest Surg 2010 May;14(5):873-9       58 Citations
1Pterostilbene inhibits breast cancer in vitro through mitochondrial depolarization and induction of caspase-dependent apoptosis. (Alosi JA, McDonald DE, Schneider JS, Privette AR, McFadden DW) J Surg Res 2010 Jun 15;161(2):195-201       95 Citations
1Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia. (Pulikkan JA, Dengler V, Peramangalam PS, Peer Zada AA, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G) Blood 2010 Mar 04;115(9):1768-78       267 Citations
2E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. (Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G) Nature 2009 Dec 17;462(7275):930-4       208 Citations
1Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. (Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK) Mol Cancer Ther 2009 Nov;8(11):3117-29       216 Citations
2Emerging roles of E2Fs in cancer: an exit from cell cycle control. (Chen HZ, Tsai SY, Leone G) Nat Rev Cancer 2009 Nov;9(11):785-97       898 Citations
1Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling. (Hong SK, Yoon S, Moelling C, Arthan D, Park JI) J Biol Chem 2009 Nov 27;284(48):33006-18       77 Citations
1Cytoskeletal control of growth and cell fate switching. (Mammoto A, Ingber DE) Curr Opin Cell Biol 2009 Dec;21(6):864-70       193 Citations
1Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus. (Hill MN, Titterness AK, Morrish AC, Carrier EJ, Lee TT, Gil-Mohapel J, Gorzalka BB, Hillard CJ, Christie BR) Hippocampus 2010 Apr;20(4):513-23       119 Citations
1p21 Expression by human urothelial carcinoma cells modulates the phenotypic response to BCG. (See WA, Zhang G, Chen F, Cao Y) Urol Oncol 2010;28(5):526-33       12 Citations
1Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells. (Benavente S, Huang S, Armstrong EA, Chi A, Hsu KT, Wheeler DL, Harari PM) Clin Cancer Res 2009 Mar 01;15(5):1585-92       88 Citations
1Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. (Safi R, Muramoto GG, Salter AB, Meadows S, Himburg H, Russell L, Daher P, Doan P, Leibowitz MD, Chao NJ, McDonnell DP, Chute JP) Mol Endocrinol 2009 Feb;23(2):188-201       24 Citations
1Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient. (Del Bene F, Wehman AM, Link BA, Baier H) Cell 2008 Sep 19;134(6):1055-65       275 Citations
2Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. (Mammoto A, Sero JE, Mammoto T, Ingber DE) Methods Enzymol 2008;443:227-59       9 Citations
1Factorial microarray analysis of zebrafish retinal development. (Leung YF, Ma P, Link BA, Dowling JE) Proc Natl Acad Sci U S A 2008 Sep 02;105(35):12909-14       39 Citations
1Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development. (Hu Z, Liu Y, Zhang C, Zhao Y, He W, Han L, Yang L, Hopkins KM, Yang X, Lieberman HB, Hang H) Cancer Res 2008 Jul 15;68(14):5552-61       31 Citations
1Many forkheads in the road to regulation. Symposium on forkhead transcription factor networks in development, signalling and disease. (Cirillo LA, Barton MC) EMBO Rep 2008 Aug;9(8):721-4       10 Citations
1Chromatin opening and stable perturbation of core histone:DNA contacts by FoxO1. (Hatta M, Cirillo LA) J Biol Chem 2007 Dec 07;282(49):35583-93       109 Citations
1Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis. (Opavsky R, Tsai SY, Guimond M, Arora A, Opavska J, Becknell B, Kaufmann M, Walton NA, Stephens JA, Fernandez SA, Muthusamy N, Felsher DW, Porcu P, Caligiuri MA, Leone G) Proc Natl Acad Sci U S A 2007 Sep 25;104(39):15400-5       54 Citations
2Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways. (Kotamraju S, Williams CL, Kalyanaraman B) Cancer Res 2007 Aug 01;67(15):7386-94       143 Citations
1Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a. (Chen D, Opavsky R, Pacal M, Tanimoto N, Wenzel P, Seeliger MW, Leone G, Bremner R) PLoS Biol 2007 Jul;5(7):e179       78 Citations
1Nuclear migration during retinal development. (Baye LM, Link BA) Brain Res 2008 Feb 04;1192:29-36       114 Citations
1Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. (McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS) Mol Cell Biol 2007 Jul;27(13):4825-43       76 Citations
1The disarrayed mutation results in cell cycle and neurogenesis defects during retinal development in zebrafish. (Baye LM, Link BA) BMC Dev Biol 2007 Apr 05;7:28       19 Citations
1Differential activity of sulindac metabolites against squamous cell carcinoma of the head and neck is mediated by p21waf1/cip1 induction and cell cycle inhibition. (Bock JM, Menon SG, Goswami PC, Sinclair LL, Bedford NS, Jackson RE, Trask DK) Cancer Biol Ther 2007 Jan;6(1):30-9       12 Citations
1Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation. (Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G) J Biol Chem 2006 Nov 24;281(47):36124-31       66 Citations
1Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer. (Strock CJ, Park JI, Rosen DM, Ruggeri B, Denmeade SR, Ball DW, Nelkin BD) J Clin Endocrinol Metab 2006 Jan;91(1):79-84       44 Citations
1Effect of mifepristone on proliferation and apoptosis of Ishikawa endometrial adenocarcinoma cells. (Li A, Felix JC, Minoo P, Amezcua CA, Jain JK) Fertil Steril 2005 Jul;84(1):202-11       39 Citations
1BCG directly induces cell cycle arrest in human transitional carcinoma cell lines as a consequence of integrin cross-linking. (Chen F, Zhang G, Iwamoto Y, See WA) BMC Urol 2005 May 12;5:8       51 Citations
1Mechanism of human SIRT1 activation by resveratrol. (Borra MT, Smith BC, Denu JM) J Biol Chem 2005 Apr 29;280(17):17187-95       1016 Citations
1IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells. (Kim EJ, Park JI, Nelkin BD) J Biol Chem 2005 Feb 11;280(6):4913-20       50 Citations
1Aberrant regulation of survivin by the RB/E2F family of proteins. (Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA) J Biol Chem 2004 Sep 24;279(39):40511-20       153 Citations
1Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. (Mammoto A, Huang S, Moore K, Oh P, Ingber DE) J Biol Chem 2004 Jun 18;279(25):26323-30       197 Citations
1Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells. (Cheng S, Hsia CY, Leone G, Liou HC) Oncogene 2003 Nov 20;22(52):8472-86       48 Citations
1Non-small and small cell lung carcinoma cell lines exhibit cell type-specific sensitivity to edelfosine-induced cell death and different cell line-specific responses to edelfosine treatment. (Shafer SH, Williams CL) Int J Oncol 2003 Aug;23(2):389-400       20 Citations
1Inactivation of E2F3 results in centrosome amplification. (Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G) Cancer Cell 2003 Apr;3(4):333-46       65 Citations
1Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines. (Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P) Clin Cancer Res 2003 Mar;9(3):969-75       27 Citations
1The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway. (Park JI, Strock CJ, Ball DW, Nelkin BD) Mol Cell Biol 2003 Jan;23(2):543-54       114 Citations
1Flow cytometry analysis of proliferative lesions at the gastrocystoplasty anastomosis. (Close CE, Tekgul S, Ganesan GS, True LD, Mitchell ME) J Urol 2003 Jan;169(1):365-8       8 Citations
1Equivalence of the linear-quadratic and two-lesion kinetic models. (Guerrero M, Stewart RD, Wang JZ, Li XA) Phys Med Biol 2002 Sep 07;47(17):3197-209       33 Citations
1Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload. (Ecarnot-Laubriet A, Assem M, Poirson-Bichat F, Moisant M, Bernard C, Lecour S, Solary E, Rochette L, Teyssier JR) Biochim Biophys Acta 2002 Apr 24;1586(3):233-42       28 Citations
1Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations. (Rozenblatt-Rosen O, Mosonego-Ornan E, Sadot E, Madar-Shapiro L, Sheinin Y, Ginsberg D, Yayon A) J Cell Sci 2002 Feb 01;115(Pt 3):553-62       56 Citations
1Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. (Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP) J Biol Chem 2002 May 10;277(19):16464-9       225 Citations
1DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (Lan Z, Sever-Chroneos Z, Strobeck MW, Park CH, Baskaran R, Edelmann W, Leone G, Knudsen ES) J Biol Chem 2002 Mar 08;277(10):8372-81       56 Citations
1Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells. (Clay CE, Namen AM, Atsumi G, Trimboli AJ, Fonteh AN, High KP, Chilton FH) J Investig Med 2001 Sep;49(5):413-20       64 Citations
1Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. (Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, Nevins JR) Mol Cell Biol 2001 Jul;21(14):4684-99       522 Citations
1Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death. (Weng LP, Gimm O, Kum JB, Smith WM, Zhou XP, Wynford-Thomas D, Leone G, Eng C) Hum Mol Genet 2001 Feb 01;10(3):251-8       83 Citations
1Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway. (Smith DS, Leone G, DeGregori J, Ahmed MN, Qumsiyeh MB, Nevins JR) Cell Growth Differ 2000 Dec;11(12):625-33       40 Citations
1Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells. (Carpenter PA, Pavlovic S, Tso JY, Press OW, Gooley T, Yu XZ, Anasetti C) J Immunol 2000 Dec 01;165(11):6205-13       95 Citations
1Posttranslational modification of TEL and TEL/AML1 by SUMO-1 and cell-cycle-dependent assembly into nuclear bodies. (Chakrabarti SR, Sood R, Nandi S, Nucifora G) Proc Natl Acad Sci U S A 2000 Nov 21;97(24):13281-5       104 Citations
1Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. (Adams MR, Sears R, Nuckolls F, Leone G, Nevins JR) Mol Cell Biol 2000 May;20(10):3633-9       123 Citations
1Enhancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab')2. (Yu XZ, Anasetti C) Transplantation 2000 Jan 15;69(1):104-12       16 Citations
1Influence of coenzyme A-independent transacylase and cyclooxygenase inhibitors on the proliferation of breast cancer cells. (Trimboli AJ, Waite BM, Atsumi G, Fonteh AN, Namen AM, Clay CE, Kute TE, High KP, Willingham MC, Chilton FH) Cancer Res 1999 Dec 15;59(24):6171-7       29 Citations
1Prognostic factors in resectable pancreatic cancer: p53 and bcl-2. (Bold RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA, Jennings M, McConkey DJ, Bucana CD, Cleary KR, Hallin PA, Chiao PJ, Abbruzzese JL, Evans DB) J Gastrointest Surg 1999;3(3):263-77       45 Citations
1Regulation of human papillomavirus type 31 polyadenylation during the differentiation-dependent life cycle. (Terhune SS, Milcarek C, Laimins LA) J Virol 1999 Sep;73(9):7185-92       45 Citations
1Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle. (Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB) Ann N Y Acad Sci 1999 Jun 30;880:31-7       31 Citations
1Cloning, expression, and in vitro activity of human endostatin. (Dhanabal M, Volk R, Ramchandran R, Simons M, Sukhatme VP) Biochem Biophys Res Commun 1999 May 10;258(2):345-52       199 Citations
1Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells. (Janssen YM, Soultanakis R, Steece K, Heerdt E, Singh RJ, Joseph J, Kalyanaraman B) Am J Physiol 1998 Dec;275(6):L1100-9       54 Citations
1Mutation, cell kinetics, and subpopulations at risk for colon cancer in the United States. (Herrero-Jimenez P, Thilly G, Southam PJ, Tomita-Mitchell A, Morgenthaler S, Furth EE, Thilly WG) Mutat Res 1998 May 25;400(1-2):553-78       45 Citations
1E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. (Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams RS, Nevins JR) Genes Dev 1998 Jul 15;12(14):2120-30       342 Citations
1Cell cycle regulation of human pancreatic cancer by tamoxifen. (Robinson EK, Grau AM, Evans DB, Smid CM, Chiao PJ, Abbruzzese JL, Grimm EA) Ann Surg Oncol 1998 Jun;5(4):342-9       20 Citations
1Cell and molecular biology of kidney development. (Orellana SA, Avner ED) Semin Nephrol 1998 May;18(3):233-43       29 Citations
1Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. (Yan Z, DeGregori J, Shohet R, Leone G, Stillman B, Nevins JR, Williams RS) Proc Natl Acad Sci U S A 1998 Mar 31;95(7):3603-8       229 Citations
1The freeze-thaw stress response of the yeast Saccharomyces cerevisiae is growth phase specific and is controlled by nutritional state via the RAS-cyclic AMP signal transduction pathway. (Park JI, Grant CM, Attfield PV, Dawes IW) Appl Environ Microbiol 1997 Oct;63(10):3818-24       119 Citations
1Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. (Long RM, Singer RH, Meng X, Gonzalez I, Nasmyth K, Jansen RP) Science 1997 Jul 18;277(5324):383-7       444 Citations
1Distinct roles for E2F proteins in cell growth control and apoptosis. (DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR) Proc Natl Acad Sci U S A 1997 Jul 08;94(14):7245-50       631 Citations
1Mitochondria-mediated cell injury. Symposium overview. (Wallace KB, Eells JT, Madeira VM, Cortopassi G, Jones DP) Fundam Appl Toxicol 1997 Jul;38(1):23-37       149 Citations
1Cell-cycle regulated expression of Rap1 in regenerating liver. (Cruise JL, Rafferty MP, Riehle MM) Biochem Biophys Res Commun 1997 Jan 23;230(3):578-81       1 Citation
1Functional analysis of E2F transcription factor. (Nevins JR, DeGregori J, Jakoi L, Leone G) Methods Enzymol 1997;283:205-19       74 Citations
1The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. (Smith EJ, Leone G, DeGregori J, Jakoi L, Nevins JR) Mol Cell Biol 1996 Dec;16(12):6965-76       210 Citations
1Induction of apoptosis by anti-CD3 epsilon F(ab')2 in antigen receptor transgenic murine T cells activated by specific peptide. (Yu XZ, Zhu L, Davis JE, Tso JY, Hansen JA, Anasetti C) J Immunol 1996 Oct 15;157(8):3420-9       20 Citations
1Cell cycle control of T cell apoptosis induced by activation through the T cell antigen receptor. (Chalupny NJ, Zhu L, Yu XZ, Anasetti C) Adv Exp Med Biol 1996;406:57-67    
1UV-induced changes in cell cycle and gene expression within rabbit lens epithelial cells. (Sidjanin D, Grdina D, Woloschak GE) Photochem Photobiol 1996 Jan;63(1):79-85       10 Citations
1Circumvention of confluence-dependent resistance in a human multi-drug-resistant colon-cancer cell line. (Garrido C, Chauffert B, Pinard D, Tibaut F, Genne P, Assem M, Dimanche-Boitrel MT) Int J Cancer 1995 Jun 09;61(6):873-9       24 Citations
1Cell cycle-related shifts in subcellular localization of BCR: association with mitotic chromosomes and with heterochromatin. (Wetzler M, Talpaz M, Yee G, Stass SA, Van Etten RA, Andreeff M, Goodacre AM, Kleine HD, Mahadevia RK, Kurzrock R) Proc Natl Acad Sci U S A 1995 Apr 11;92(8):3488-92       23 Citations
1Analysis of exposure times and dose escalation of paclitaxel in ovarian cancer cell lines. (Adler LM, Herzog TJ, Williams S, Rader JS, Mutch DG) Cancer 1994 Oct 01;74(7):1891-8       25 Citations
1Limited cell-cycle dependence of the merocyanine 540-sensitized photoinactivation of L1210 leukemia cells. (Qiu K, Traul DL, Sieber F) Photochem Photobiol 1992 Aug;56(2):277-80       2 Citations
1Comparison of in vivo and in vitro effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with acute myeloid leukemia. (Estrov Z, Estey EH, Andreeff M, Talpaz M, Kurzrock R, Reading CL, Deisseroth AB, Gutterman JU) Exp Hematol 1992 Jun;20(5):558-64       16 Citations
1Activation of muscarinic acetylcholine receptors inhibits cell cycle progression of small cell lung carcinoma. (Williams CL, Lennon VA) Cell Regul 1991 May;2(5):373-81       44 Citations
1Effect of hair growth cycles on experimental cutaneous candidiasis in mice. (Sohnle PG, Collins-Lech C, Hahn B) J Invest Dermatol 1986 May;86(5):556-9       8 Citations
1Comparative studies on highly metabolically active histone acetylation. (Moore M, Jackson V, Sealy L, Chalkley R) Biochim Biophys Acta 1979 Jan 26;561(1):248-60       43 Citations